Epidemiology of prepubertal testicular and paratesticular tumors in public hospitals
DOI:
https://doi.org/10.62428/rcvp2025411984Keywords:
Testicular and paratesticular tumors, alpha-fetoprotein, teratomaAbstract
The objective was to analyze the different types of prepubertal testicular and paratesticular tumors to establish treatment guidelines at the Hospital Nacional Edgardo Rebagliati Martins (HNERM) and the Instituto Nacional de Salud del Niño (INSN) from 2000 to 2022. A retro-prospective series of 59 prepubertal patients diagnosed with testicular or paratesticular tumors is presented. To identify the characteristics of the different tumor types, ultrasounds, X-rays, tumor markers, and CT scans were applied. A series of 59 patients is presented. It was found that 43 (73%) patients had yolk sac tumors (YST), 10 (17%) had mature teratomas, 1 (2%) had an immature teratoma, 4 (7%) had embryonal rhabdomyosarcoma, and 1 (2%) had a Sertoli cell tumor. The most frequent age of presentation was one year old; among the 23 patients from HNERM, 19 (83%) were in clinical stage I, mostly YSTs, 3 (13%) were stage II (YST), and 1 (4%) was stage IV (YST); alpha-fetoprotein levels were elevated in patients with YST; in two patients with mature cystic teratoma, testis-sparing surgery was performed with favorable outcomes; five patients received chemotherapy (1 rhabdomyosarcoma, 4 YST); in the stage IV YST case, an abdominal tumorectomy was also performed. Testicular and paratesticular tumors in prepubertal boys present epidemiological, histological, developmental, and therapeutic characteristics that are distinct from those found in postpubertal patients. Testis-sparing surgery should be considered for benign tumors.
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