Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 |e- issn 2311-2212 17
Panorama de la pandemia COVID-19
Landscape of COVID-19 pandemic
๎™ฒ๎ „๎ขฌ๎ก™๎กป๎ดฎ๎šฎ๎ …๎กป๎ ข๎ก’๎ ฐ๎ฃต๎ดŒ๎˜‚๎™ฟ๎ ก๎ ฐ๎ขฌ๎ฃ€๎ณ 
๎ดŒA
๎šฆ๎ข…๎ ฉ๎ขฌ๎ก—๎ก‹๎ฃˆ๎ ฐ๎ฃต๎ดฎ๎™จ๎ „๎กป๎ ฉ๎ „๎ฃˆ๎ขฌ๎ข…๎ดŒ๎˜‚๎˜ƒ๎กป๎ „๎ดฎ๎™ค๎ฃˆ๎กฐ๎ก—๎ ฐ๎ฃ€๎ณก
๎™ฒ๎ „๎ขฌ๎ก™๎กป๎ดฎ๎™ฒ๎ „๎ ข๎ก’๎ฃˆ๎ ข๎ „๎ดŒ๎˜‚๎™ฟ๎กฐ๎ ฐ๎ก‹๎ „๎ขฌ๎ก—๎ข…
๎ฒœ
๎™ฒ๎ „๎ขฌ๎ก™๎กป๎ดฎ๎šฎ๎ …๎กป๎ ข๎ก’๎ ฐ๎ฃต๎ดŒ๎˜‚๎›ƒ๎กฐ๎ ฐ๎ขฌ๎ฃ€
๎ฒ
๎™‡๎ „๎กน๎ ฐ๎ขฌ๎ข…๎˜‚๎˜ ๎ดŒ๎˜‚๎˜Ÿ๎ ฐ๎ฃ€๎ฃ€๎ฃซ๎˜‚๎˜ฏ๎ด’
๎ฒž
๎›Ÿ๎ ฑ๎ขฌ๎ฃ€๎ก—๎ฃต๎˜‚๎™ฟ๎ขด๎ข…๎ขฌ๎ ฐ๎ขด๎ดŒ๎˜‚๎™ค๎ „๎ ข๎ก—๎กป๎ฃ€๎ข…๎˜‚๎™ค๎ข…๎ „๎ขซ๎ฃˆ๎ก—๎กป
๎ฒŸ
ABSTRACT
๎ ƒ๎œฉ๎˜‚ ๎› ๎ป๎žข๎ฆ๎œข๎˜‚ ๎™Ž๎œฉ๎›พ๎ฆ๎žท๎‰๎˜‚ ๎™ฟ๎žข๎‚๎›พ๎ฑ๎Ž๎Ÿฌ๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚ ๎žข๎œฉ๎œ›๎œฉ๎Ž๎Ÿ›๎œฉ๎œข๎˜‚ ๎›พ๎˜‚ ๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎˜‚ ๎๎žข๎ป๎ฏ๎˜‚ ๎žท๎‰๎œฉ๎˜‚
๎šฃ๎œฉ๎ป๎žŸ๎ฆ๎œฉ๎ดผ๎žช๎˜‚๎šฆ๎œฉ๎žŸ๎žฟ๎œš๎ฆ๎Ž๎œ›๎˜‚๎ป๎๎˜‚๎˜ ๎‰๎Ž๎ฑ๎›พ๎˜‚๎ป๎ฑ๎˜‚๎›พ๎žท๎Ÿข๎žŸ๎Ž๎œ›๎›พ๎ฆ๎˜‚๎žŸ๎ฑ๎œฉ๎žฟ๎ฏ๎ป๎ฑ๎Ž๎›พ๎˜‚๎Ž๎ฑ๎˜‚๎› ๎žฟ๎‰๎›พ๎ฑ๎˜‚๎˜ ๎Ž๎žท๎Ÿข๎˜‚
๎ป๎ฑ๎˜‚๎˜ง๎œฉ๎œ›๎œฉ๎ฏ๎œš๎œฉ๎žข๎˜‚๎ฒ’๎ฒ๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ด’๎˜‚๎šฎ๎Ž๎ฑ๎œ›๎œฉ๎˜‚๎žท๎‰๎œฉ๎˜‚๎ €๎žข๎žช๎žท๎˜‚๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎˜‚๎žท๎ป๎˜‚๎œข๎›พ๎žท๎œฉ๎˜‚๎ดฃ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚๎ฒ’๎ฒ๎žท๎‰๎ดค๎ดŒ๎˜‚๎Ž๎žท๎˜‚
๎‰๎›พ๎žช๎˜‚๎œš๎œฉ๎œฉ๎ฑ๎˜‚๎ฒ๎ฒ๎ฒ”๎˜‚๎œข๎›พ๎Ÿข๎žช๎ดŒ๎˜‚๎›พ๎ฑ๎œข๎˜‚๎ฆ๎Ž๎žท๎žท๎ฆ๎œฉ๎˜‚๎Ÿœ๎œฉ๎˜‚๎ฃ๎ฑ๎ป๎Ÿœ๎˜‚๎›พ๎œš๎ป๎žฟ๎žท๎˜‚๎žท๎‰๎œฉ๎˜‚๎ฑ๎œฉ๎Ÿœ๎˜‚๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚
๎ดฃ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎ดค๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎œข๎Ž๎žช๎œฉ๎›พ๎žช๎œฉ๎ด’๎˜‚ ๎˜ฏ๎žŸ๎Ž๎œข๎œฉ๎ฏ๎Ž๎ป๎ฆ๎ป๎‚๎Ž๎œ›๎›พ๎ฆ๎˜‚ ๎žช๎žท๎žฟ๎œข๎Ž๎œฉ๎žช๎˜‚
๎Ž๎ฑ๎˜‚ ๎žข๎œฉ๎œ›๎œฉ๎ฑ๎žท๎˜‚ ๎Ÿข๎œฉ๎›พ๎žข๎žช๎˜‚ ๎Ÿœ๎œฉ๎žข๎œฉ๎˜‚ ๎›พ๎ฆ๎žข๎œฉ๎›พ๎œข๎Ÿข๎˜‚ ๎›พ๎ฆ๎œฉ๎žข๎žท๎Ž๎ฑ๎‚๎˜‚ ๎›พ๎œš๎ป๎žฟ๎žท๎˜‚ ๎ฑ๎œฉ๎Ÿœ๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚
๎ป๎žฟ๎žท๎œš๎žข๎œฉ๎›พ๎ฃ๎žช๎ดŒ๎˜‚๎œš๎žฟ๎žท๎˜‚๎Ÿœ๎œฉ๎žข๎œฉ๎˜‚๎ฑ๎ป๎žท๎˜‚๎žท๎›พ๎ฃ๎œฉ๎ฑ๎˜‚๎Ž๎ฑ๎žท๎ป๎˜‚๎œ›๎ป๎ฑ๎žช๎Ž๎œข๎œฉ๎žข๎›พ๎žท๎Ž๎ป๎ฑ๎ดŒ๎˜‚๎›พ๎ฑ๎œข๎˜‚๎žท๎‰๎Ž๎žช๎˜‚๎žข๎œฉ๎žช๎žฟ๎ฆ๎žท๎œฉ๎œข๎˜‚
๎Ž๎ฑ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎œš๎œฉ๎Ž๎ฑ๎‚๎˜‚๎žท๎‰๎œฉ๎˜‚๎ €๎žข๎žช๎žท๎˜‚๎œš๎œฉ๎žท๎›พ๎ดฎ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎žท๎ป๎˜‚๎žข๎œฉ๎›พ๎œ›๎‰๎˜‚๎žŸ๎›พ๎ฑ๎œข๎œฉ๎ฏ๎Ž๎œ›๎˜‚
๎žช๎žท๎›พ๎žท๎žฟ๎žช๎ด’๎˜‚๎˜ง๎Ž๎›พ๎‚๎ฑ๎ป๎žช๎Ž๎žช๎˜‚๎Ž๎žช๎˜‚๎œš๎›พ๎žช๎œฉ๎œข๎˜‚๎ป๎ฑ๎˜‚๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎˜‚๎œฉ๎Ÿ›๎Ž๎œข๎œฉ๎ฑ๎œ›๎œฉ๎˜‚๎›พ๎‚๎›พ๎Ž๎ฑ๎žช๎žท๎˜‚๎žท๎‰๎œฉ๎˜‚๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚
๎›พ๎ฑ๎œข๎˜‚๎žช๎œฉ๎žข๎ป๎ฆ๎ป๎‚๎Ž๎œ›๎›พ๎ฆ๎˜‚๎žท๎œฉ๎žช๎žท๎žช๎˜‚๎๎ป๎žข๎˜‚๎žท๎‰๎œฉ๎˜‚ ๎œข๎Ž๎žช๎œฉ๎›พ๎žช๎œฉ๎ด’๎˜‚๎™“๎ฑ๎˜‚๎›พ๎œข๎œข๎Ž๎žท๎Ž๎ป๎ฑ๎ดŒ๎˜‚๎ฆ๎Ž๎žท๎žท๎ฆ๎œฉ๎˜‚๎Ž๎žช๎˜‚๎ฃ๎ฑ๎ป๎Ÿœ๎ฑ๎˜‚
๎›พ๎œš๎ป๎žฟ๎žท๎˜‚ ๎žท๎‰๎œฉ๎˜‚ ๎ฏ๎œฉ๎œ›๎‰๎›พ๎ฑ๎Ž๎žช๎ฏ๎žช๎˜‚ ๎ป๎๎˜‚ ๎œ›๎ป๎ฑ๎žท๎›พ๎‚๎Ž๎ป๎ฑ๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎žช๎Ž๎ป๎ฑ๎ดŒ๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎Ž๎ฑ๎˜‚
๎žท๎žฟ๎žข๎ฑ๎˜‚๎žท๎‰๎œฉ๎˜‚๎œ›๎œฉ๎ฆ๎ฆ๎žฟ๎ฆ๎›พ๎žข๎˜‚๎›พ๎ฑ๎œข๎˜‚๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎˜‚๎ฏ๎œฉ๎œ›๎‰๎›พ๎ฑ๎Ž๎žช๎ฏ๎žช๎˜‚๎žฟ๎žช๎œฉ๎œข๎˜‚๎œš๎Ÿข๎˜‚๎žท๎‰๎œฉ๎˜‚๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎๎ป๎žข๎˜‚
๎Ž๎ฑ๎๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎ดŒ๎˜‚๎›พ๎ฑ๎œข๎˜‚๎›พ๎œš๎ป๎žฟ๎žท๎˜‚ ๎Ž๎ฏ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚๎žข๎œฉ๎žช๎žŸ๎ป๎ฑ๎žช๎œฉ๎˜‚๎ฏ๎œฉ๎œ›๎‰๎›พ๎ฑ๎Ž๎žช๎ฏ๎žช๎˜‚๎›พ๎žข๎œฉ๎˜‚๎ฃ๎ฑ๎ป๎Ÿœ๎ฑ๎ด’๎˜‚
๎™†๎Ž๎ฑ๎›พ๎ฆ๎ฆ๎Ÿข๎ดŒ๎˜‚ ๎œ›๎žฟ๎žข๎žข๎œฉ๎ฑ๎žท๎˜‚ ๎œฉ๎Ÿฒ๎๎ป๎žข๎žท๎žช๎˜‚ ๎›พ๎žข๎œฉ๎˜‚ ๎๎ป๎œ›๎žฟ๎žช๎œฉ๎œข๎˜‚ ๎ป๎ฑ๎˜‚ ๎œฉ๎Ÿฒ๎๎œฉ๎œ›๎žท๎Ž๎Ÿ›๎œฉ๎˜‚ ๎žท๎žข๎œฉ๎›พ๎žท๎ฏ๎œฉ๎ฑ๎žท๎žช๎˜‚ ๎›พ๎ฑ๎œข๎˜‚
๎Ÿ›๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚๎œข๎œฉ๎Ÿ›๎œฉ๎ฆ๎ป๎žŸ๎ฏ๎œฉ๎ฑ๎žท๎ด—๎˜‚๎œš๎žฟ๎žท๎˜‚๎ฑ๎ป๎Ÿœ๎˜‚๎žท๎‰๎œฉ๎žข๎œฉ๎˜‚๎›พ๎žข๎œฉ๎˜‚๎ป๎ฑ๎ฆ๎Ÿข๎˜‚๎Ÿ›๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚๎œ›๎›พ๎ฑ๎œข๎Ž๎œข๎›พ๎žท๎œฉ๎žช๎˜‚
๎Ÿœ๎‰๎Ž๎œ›๎‰๎˜‚๎›พ๎žข๎œฉ๎˜‚๎žช๎žท๎Ž๎ฆ๎ฆ๎˜‚๎Ž๎ฑ๎˜‚๎žท๎‰๎œฉ๎˜‚๎œ›๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎˜‚๎žข๎œฉ๎žช๎œฉ๎›พ๎žข๎œ›๎‰๎˜‚๎žŸ๎‰๎›พ๎žช๎œฉ๎˜‚๎›พ๎ฑ๎œข๎˜‚๎žช๎žท๎Ž๎ฆ๎ฆ๎˜‚๎žข๎œฉ๎žก๎žฟ๎Ž๎žข๎œฉ๎˜‚๎ฏ๎ป๎žข๎œฉ๎˜‚
๎žท๎Ž๎ฏ๎œฉ๎˜‚๎žท๎ป๎˜‚๎œš๎œฉ๎˜‚๎›พ๎žŸ๎žŸ๎žข๎ป๎Ÿ›๎œฉ๎œข๎˜‚๎žท๎‰๎œฉ๎Ž๎žข๎˜‚๎žฟ๎žช๎œฉ๎˜‚๎Ž๎ฑ๎˜‚๎žท๎‰๎œฉ๎˜‚๎‰๎žฟ๎ฏ๎›พ๎ฑ๎˜‚๎žŸ๎ป๎žŸ๎žฟ๎ฆ๎›พ๎žท๎Ž๎ป๎ฑ๎ด’
Keywords:๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎ดŒ๎˜‚ ๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎žช๎Ž๎ป๎ฑ๎ดŒ๎˜‚ ๎Ž๎ฏ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎ป๎ฑ๎žช๎œฉ๎ดŒ๎˜‚
๎œข๎Ž๎›พ๎‚๎ฑ๎ป๎žช๎žท๎Ž๎œ›๎ดŒ๎˜‚๎Ÿ›๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎ด’
RESUMEN
๎™จ๎›พ๎˜‚ ๎™ฟ๎žข๎‚๎›พ๎ฑ๎Ž๎Ÿฌ๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚ ๎™ฒ๎žฟ๎ฑ๎œข๎Ž๎›พ๎ฆ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎šฎ๎›พ๎ฆ๎žฟ๎œข๎˜‚ ๎žข๎œฉ๎œ›๎Ž๎œš๎Ž๎ผ๎˜‚ ๎žฟ๎ฑ๎˜‚ ๎Ž๎ฑ๎๎ป๎žข๎ฏ๎œฉ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚
๎šฆ๎œฉ๎žŸ๎Ÿ€๎œš๎ฆ๎Ž๎œ›๎›พ๎˜‚๎šฃ๎ป๎žŸ๎žฟ๎ฆ๎›พ๎žข๎˜‚๎˜ ๎‰๎Ž๎ฑ๎›พ๎˜‚๎žช๎ป๎œš๎žข๎œฉ๎˜‚๎ฑ๎œฉ๎žฟ๎ฏ๎ป๎ฑ๎๎›พ๎˜‚๎›พ๎žท๎๎žŸ๎Ž๎œ›๎›พ๎˜‚๎œฉ๎ฑ๎˜‚๎ฆ๎›พ๎˜‚๎œ›๎Ž๎žฟ๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚
๎› ๎žฟ๎‰๎›พ๎ฑ๎ดŒ๎˜‚๎œฉ๎ฆ๎˜‚๎ฒ’๎ฒ๎˜‚๎œข๎œฉ๎˜‚๎œข๎Ž๎œ›๎Ž๎œฉ๎ฏ๎œš๎žข๎œฉ๎˜‚๎œข๎œฉ๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ด’๎˜‚๎˜ง๎œฉ๎žช๎œข๎œฉ๎˜‚๎œฉ๎ฆ๎˜‚๎žŸ๎žข๎Ž๎ฏ๎œฉ๎žข๎˜‚๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎œฉ๎˜‚๎‰๎›พ๎ฑ๎˜‚
๎žŸ๎›พ๎žช๎›พ๎œข๎ป๎˜‚๎ฒ๎ฒ๎ฒ”๎˜‚๎œข๎๎›พ๎žช๎˜‚๎ดฃ๎ฒ’๎ฒ๎˜‚๎œข๎œฉ๎˜‚๎›พ๎œš๎žข๎Ž๎ฆ๎ดค๎ดŒ๎˜‚๎Ÿข๎˜‚๎œฉ๎žช๎˜‚๎žŸ๎ป๎œ›๎ป๎˜‚๎ฆ๎ป๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎žช๎œฉ๎˜‚๎œ›๎ป๎ฑ๎ป๎œ›๎œฉ๎˜‚๎žช๎ป๎œš๎žข๎œฉ๎˜‚๎œฉ๎ฆ๎˜‚
๎ฑ๎žฟ๎œฉ๎Ÿ›๎ป๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎ดฃ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎ดค๎˜‚ ๎Ÿข๎˜‚ ๎ฆ๎›พ๎˜‚ ๎œฉ๎ฑ๎๎œฉ๎žข๎ฏ๎œฉ๎œข๎›พ๎œข๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ด’๎˜‚
๎™จ๎ป๎žช๎˜‚ ๎œฉ๎žช๎žท๎žฟ๎œข๎Ž๎ป๎žช๎˜‚ ๎œฉ๎žŸ๎Ž๎œข๎œฉ๎ฏ๎Ž๎ป๎ฆ๎ผ๎‚๎Ž๎œ›๎ป๎žช๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎ป๎žช๎˜‚ ๎Ÿ€๎ฆ๎žท๎Ž๎ฏ๎ป๎žช๎˜‚ ๎›พ๎บ๎ป๎žช๎˜‚ ๎Ÿข๎›พ๎˜‚ ๎›พ๎ฆ๎œฉ๎žข๎žท๎›พ๎œš๎›พ๎ฑ๎˜‚
๎žช๎ป๎œš๎žข๎œฉ๎˜‚๎ฑ๎žฟ๎œฉ๎Ÿ›๎ป๎žช๎˜‚๎œš๎žข๎ป๎žท๎œฉ๎žช๎˜‚๎œข๎œฉ๎˜‚๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎ดŒ๎˜‚๎žŸ๎œฉ๎žข๎ป๎˜‚๎ฑ๎ป๎˜‚๎๎žฟ๎œฉ๎žข๎ป๎ฑ๎˜‚๎žท๎ป๎ฏ๎›พ๎œข๎ป๎žช๎˜‚๎œฉ๎ฑ๎˜‚
๎œ›๎ป๎ฑ๎žช๎Ž๎œข๎œฉ๎žข๎›พ๎œ›๎Ž๎ผ๎ฑ๎ดŒ๎˜‚๎Ÿข๎˜‚๎œฉ๎žช๎žท๎ป๎˜‚๎œข๎Ž๎ป๎˜‚๎ฆ๎žฟ๎‚๎›พ๎žข๎˜‚๎›พ๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎žช๎œฉ๎›พ๎˜‚๎œฉ๎ฆ๎˜‚๎žŸ๎žข๎Ž๎ฏ๎œฉ๎žข๎˜‚๎œš๎œฉ๎žท๎›พ๎ดฎ
๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎›พ๎ฆ๎œ›๎›พ๎ฑ๎Ÿฌ๎›พ๎˜‚ ๎œฉ๎ฆ๎˜‚ ๎œฉ๎žช๎žท๎›พ๎œข๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎žŸ๎›พ๎ฑ๎œข๎œฉ๎ฏ๎Ž๎›พ๎ด’๎˜‚ ๎˜ฏ๎ฆ๎˜‚ ๎œข๎Ž๎›พ๎‚๎ฑ๎ผ๎žช๎žท๎Ž๎œ›๎ป๎˜‚
๎œฉ๎žช๎žท๎›ฟ๎˜‚ ๎œš๎›พ๎žช๎›พ๎œข๎ป๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎žŸ๎žข๎žฟ๎œฉ๎œš๎›พ๎žช๎˜‚ ๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎œฉ๎žช๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎œข๎œฉ๎žท๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎Ÿข๎ดŒ๎˜‚
๎œฉ๎ฑ๎˜‚ ๎žŸ๎žข๎žฟ๎œฉ๎œš๎›พ๎žช๎˜‚ ๎žช๎œฉ๎žข๎ป๎ฆ๎ผ๎‚๎Ž๎œ›๎›พ๎žช๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎œฉ๎ฑ๎๎œฉ๎žข๎ฏ๎œฉ๎œข๎›พ๎œข๎ด’๎˜‚ ๎˜ƒ๎œข๎Ž๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎žช๎œฉ๎˜‚
๎œ›๎ป๎ฑ๎ป๎œ›๎œฉ๎˜‚๎žŸ๎ป๎œ›๎ป๎˜‚๎žช๎ป๎œš๎žข๎œฉ๎˜‚๎ฆ๎ป๎žช๎˜‚๎ฏ๎œฉ๎œ›๎›พ๎ฑ๎Ž๎žช๎ฏ๎ป๎žช๎˜‚๎œข๎œฉ๎˜‚๎œ›๎ป๎ฑ๎žท๎›พ๎‚๎Ž๎ป๎˜‚๎Ÿข๎˜‚๎œข๎œฉ๎˜‚๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎ด’๎˜‚
๎˜ƒ๎Ÿ€๎ฑ๎˜‚๎žช๎œฉ๎˜‚๎œฉ๎žช๎žท๎›ฟ๎˜‚๎Ž๎ฑ๎Ÿ›๎œฉ๎žช๎žท๎Ž๎‚๎›พ๎ฑ๎œข๎ป๎˜‚๎ฆ๎ป๎žช๎˜‚๎ฏ๎œฉ๎œ›๎›พ๎ฑ๎Ž๎žช๎ฏ๎ป๎žช๎˜‚๎œ›๎œฉ๎ฆ๎žฟ๎ฆ๎›พ๎žข๎œฉ๎žช๎˜‚๎Ÿข๎˜‚๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎œฉ๎žช๎˜‚
๎žก๎žฟ๎œฉ๎˜‚ ๎œฉ๎ฏ๎žŸ๎ฆ๎œฉ๎›พ๎˜‚ ๎œฉ๎ฆ๎˜‚ ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚๎ฆ๎›พ๎˜‚ ๎Ž๎ฑ๎๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎ดŒ๎˜‚๎›พ๎œข๎Ž๎œ›๎Ž๎ป๎ฑ๎›พ๎ฑ๎œข๎ป๎˜‚ ๎ฆ๎ป๎žช๎˜‚ ๎žŸ๎žข๎ป๎œ›๎œฉ๎žช๎ป๎žช๎˜‚
๎žช๎Ž๎ฏ๎Ž๎ฆ๎›พ๎žข๎œฉ๎žช๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎žฟ๎œฉ๎žช๎žท๎›พ๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎‰๎žฟ๎ฏ๎›พ๎ฑ๎ป๎žช๎ด’๎˜‚ ๎™†๎Ž๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎ฆ๎ป๎žช๎˜‚
๎œฉ๎žช๎๎žฟ๎œฉ๎žข๎Ÿฌ๎ป๎žช๎˜‚ ๎›พ๎œ›๎žท๎žฟ๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎œฉ๎žช๎žท๎›ฟ๎ฑ๎˜‚ ๎œฉ๎ฑ๎๎ป๎œ›๎›พ๎œข๎ป๎žช๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎žท๎žข๎›พ๎žท๎›พ๎ฏ๎Ž๎œฉ๎ฑ๎žท๎ป๎žช๎˜‚ ๎œฉ๎ €๎œ›๎›พ๎œ›๎œฉ๎žช๎˜‚ ๎Ÿข๎˜‚
๎œฉ๎ฑ๎˜‚๎œฉ๎ฆ๎˜‚๎œข๎œฉ๎žช๎›พ๎žข๎žข๎ป๎ฆ๎ฆ๎ป๎˜‚๎œข๎œฉ๎˜‚๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎žช๎ด—๎˜‚๎žŸ๎œฉ๎žข๎ป๎˜‚๎žŸ๎ป๎žข๎˜‚๎œฉ๎ฆ๎˜‚๎ฏ๎ป๎ฏ๎œฉ๎ฑ๎žท๎ป๎˜‚๎žช๎ผ๎ฆ๎ป๎˜‚๎žช๎œฉ๎˜‚๎žท๎Ž๎œฉ๎ฑ๎œฉ๎ฑ๎˜‚
๎œ›๎›พ๎ฑ๎œข๎Ž๎œข๎›พ๎žท๎ป๎žช๎˜‚ ๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎›พ๎Ÿ€๎ฑ๎˜‚ ๎œฉ๎žช๎žท๎›ฟ๎ฑ๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎๎›พ๎žช๎œฉ๎˜‚ ๎œข๎œฉ๎˜‚ ๎Ž๎ฑ๎Ÿ›๎œฉ๎žช๎žท๎Ž๎‚๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚
๎œ›๎ฆ๎๎ฑ๎Ž๎œ›๎›พ๎˜‚๎Ÿข๎˜‚๎›พ๎Ÿ€๎ฑ๎˜‚๎žข๎œฉ๎žก๎žฟ๎Ž๎œฉ๎žข๎œฉ๎ฑ๎˜‚๎ฏ๎›ฟ๎žช๎˜‚๎žท๎Ž๎œฉ๎ฏ๎žŸ๎ป๎˜‚๎žŸ๎›พ๎žข๎›พ๎˜‚๎›พ๎žŸ๎žข๎ป๎œš๎›พ๎žข๎žช๎œฉ๎˜‚๎žช๎žฟ๎˜‚ ๎žฟ๎žช๎ป๎˜‚๎œฉ๎ฑ๎˜‚๎ฆ๎›พ๎˜‚
๎žŸ๎ป๎œš๎ฆ๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎‰๎žฟ๎ฏ๎›พ๎ฑ๎›พ๎ด’
Palabras clave: ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎ดŒ๎˜‚ ๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎ดŒ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎žฟ๎œฉ๎žช๎žท๎›พ๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎œฉ๎ดŒ๎˜‚
๎œข๎Ž๎›พ๎‚๎ฑ๎ผ๎žช๎žท๎Ž๎œ›๎ป๎ดŒ๎˜‚๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎ด’
๎ฒ๎ด’๎˜‚ ๎˜ง๎œฉ๎žŸ๎›พ๎žข๎žท๎›พ๎ฏ๎œฉ๎ฑ๎žท๎ป๎˜‚ ๎˜ƒ๎œ›๎›พ๎œข๎œช๎ฏ๎Ž๎œ›๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎™ฒ๎Ž๎œ›๎žข๎ป๎œš๎Ž๎ป๎ฆ๎ป๎‚๎๎›พ๎˜‚ ๎™ฒ๎œช๎œข๎Ž๎œ›๎›พ๎ดŒ๎˜‚
๎™†๎›พ๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎™ฒ๎œฉ๎œข๎Ž๎œ›๎Ž๎ฑ๎›พ๎ดŒ๎˜‚๎›ƒ๎ฑ๎Ž๎Ÿ›๎œฉ๎žข๎žช๎Ž๎œข๎›พ๎œข๎˜‚๎™ด๎›พ๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚๎™ฒ๎›พ๎Ÿข๎ป๎žข๎˜‚๎œข๎œฉ๎˜‚๎šฎ๎›พ๎ฑ๎˜‚
๎™ฒ๎›พ๎žข๎œ›๎ป๎žช๎ด’๎˜‚๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
๎ฒ‘๎ด’๎˜‚ ๎šฆ๎œฉ๎œข๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎›พ๎ฆ๎žฟ๎œข๎˜‚ ๎™Ž๎žฟ๎›พ๎žข๎ป๎œ›๎‰๎Ž๎žข๎๎ด’๎˜‚ ๎™ฒ๎Ž๎ฑ๎Ž๎žช๎žท๎œฉ๎žข๎Ž๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎›พ๎ฆ๎žฟ๎œข๎˜‚ ๎ดฃ๎™ฒ๎™“๎™ด๎šฎ๎˜ƒ๎ดค๎ด’๎˜‚
๎™จ๎Ž๎ฏ๎›พ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
๎ฒ’๎ด’๎˜‚ ๎˜ง๎œฉ๎žŸ๎›พ๎žข๎žท๎›พ๎ฏ๎œฉ๎ฑ๎žท๎ป๎˜‚ ๎˜ƒ๎œ›๎›พ๎œข๎œช๎ฏ๎Ž๎œ›๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎˜ ๎Ž๎œฉ๎ฑ๎œ›๎Ž๎›พ๎žช๎˜‚ ๎˜ƒ๎ฆ๎Ž๎ฏ๎œฉ๎ฑ๎žท๎›พ๎žข๎Ž๎›พ๎žช๎ดŒ๎˜‚
๎™†๎›พ๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎™ฟ๎œ›๎œฉ๎›พ๎ฑ๎ป๎‚๎žข๎›พ๎๎๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žช๎žก๎žฟ๎œฉ๎žข๎๎›พ๎ดŒ๎˜‚๎˜ ๎Ž๎œฉ๎ฑ๎œ›๎Ž๎›พ๎žช๎˜‚๎˜ƒ๎ฆ๎Ž๎ฏ๎œฉ๎ฑ๎žท๎›พ๎žข๎Ž๎›พ๎žช๎˜‚
๎Ÿข๎˜‚ ๎˜ƒ๎œ›๎žฟ๎Ž๎œ›๎žฟ๎ฆ๎žท๎žฟ๎žข๎›พ๎ดŒ๎˜‚ ๎›ƒ๎ฑ๎Ž๎Ÿ›๎œฉ๎žข๎žช๎Ž๎œข๎›พ๎œข๎˜‚ ๎™ด๎›พ๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚ ๎™†๎œฉ๎œข๎œฉ๎žข๎Ž๎œ›๎ป๎˜‚ ๎›Ÿ๎Ž๎ฆ๎ฆ๎›พ๎žข๎žข๎œฉ๎›พ๎ฆ๎ด’๎˜‚
๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
๎ฒ“๎ด’๎˜‚ ๎˜ง๎Ž๎žข๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚๎™‡๎œฉ๎ฑ๎œฉ๎žข๎›พ๎ฆ๎˜‚๎œข๎œฉ๎˜‚๎˜ƒ๎žช๎žฟ๎ฑ๎žท๎ป๎žช๎˜‚๎˜ƒ๎ฏ๎œš๎Ž๎œฉ๎ฑ๎žท๎›พ๎ฆ๎œฉ๎žช๎ด’๎˜‚๎™ฒ๎Ž๎ฑ๎Ž๎žช๎žท๎œฉ๎žข๎Ž๎ป๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚
๎šฃ๎žข๎ป๎œข๎žฟ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚๎ดฃ๎šฃ๎šฆ๎™ฟ๎˜ง๎›ƒ๎˜ ๎˜ฏ๎ดค๎ด’๎˜‚๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
๎ฒ”๎ด’๎˜‚ ๎™จ๎›พ๎œš๎ป๎žข๎›พ๎žท๎ป๎žข๎Ž๎ป๎˜‚๎œข๎œฉ๎˜‚๎™‡๎œฉ๎ฑ๎œช๎žท๎Ž๎œ›๎›พ๎˜‚๎˜ƒ๎žŸ๎ฆ๎Ž๎œ›๎›พ๎œข๎›พ๎ด’๎˜‚๎™†๎›พ๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎™ฟ๎œ›๎œฉ๎›พ๎ฑ๎ป๎‚๎žข๎›พ๎๎๎›พ๎ดŒ๎˜‚
๎šฃ๎œฉ๎žช๎žก๎žฟ๎œฉ๎žข๎๎›พ๎ดŒ๎˜‚๎˜ ๎Ž๎œฉ๎ฑ๎œ›๎Ž๎›พ๎žช๎˜‚๎˜ƒ๎ฆ๎Ž๎ฏ๎œฉ๎ฑ๎žท๎›พ๎žข๎Ž๎›พ๎žช๎˜‚๎Ÿข๎˜‚๎˜ƒ๎œ›๎žฟ๎Ž๎œ›๎žฟ๎ฆ๎žท๎žฟ๎žข๎›พ๎ดŒ๎˜‚๎›ƒ๎ฑ๎Ž๎Ÿ›๎œฉ๎žข๎žช๎Ž๎œข๎›พ๎œข๎˜‚
๎™ด๎›พ๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚๎™†๎œฉ๎œข๎œฉ๎žข๎Ž๎œ›๎ป๎˜‚๎›Ÿ๎Ž๎ฆ๎ฆ๎›พ๎žข๎žข๎œฉ๎›พ๎ฆ๎ด’๎˜‚๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
๎ฒ•๎ด’๎˜‚ ๎™†๎›พ๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚ ๎œข๎œฉ๎˜‚ ๎™“๎ฑ๎‚๎œฉ๎ฑ๎Ž๎œฉ๎žข๎๎›พ๎˜‚ ๎Ÿข๎˜‚ ๎™‡๎œฉ๎žช๎žท๎Ž๎ผ๎ฑ๎ด’๎˜‚ ๎˜ฏ๎žช๎œ›๎žฟ๎œฉ๎ฆ๎›พ๎˜‚ ๎šฃ๎žข๎ป๎๎œฉ๎žช๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚ ๎œข๎œฉ๎˜‚
๎™“๎ฑ๎‚๎œฉ๎ฑ๎Ž๎œฉ๎žข๎๎›พ๎˜‚๎˜ƒ๎ฏ๎œš๎Ž๎œฉ๎ฑ๎žท๎›พ๎ฆ๎ด’๎˜‚๎›ƒ๎ฑ๎Ž๎Ÿ›๎œฉ๎žข๎žช๎Ž๎œข๎›พ๎œข๎˜‚๎™ด๎›พ๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚๎šผ๎œฉ๎œ›๎ฑ๎ป๎ฆ๎ผ๎‚๎Ž๎œ›๎›พ๎˜‚๎œข๎œฉ๎˜‚
๎™จ๎Ž๎ฏ๎›พ๎˜‚๎šฎ๎žฟ๎žข๎ด’๎˜‚๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€
A
ORCID: ๎ฒ™๎ฒ™๎ฒ™๎ฒ™๎ดณ๎ฒ™๎ฒ™๎ฒ™๎ฒœ๎ดณ๎ฒ›๎ฒข๎ฒš๎ฒ›๎ดณ๎ฒš๎ฒš๎ฒข๎ฒš
๎˜ ๎ป๎žข๎žข๎œฉ๎žช๎žŸ๎ป๎ฑ๎œข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎ด‹๎˜‚๎ป๎ฏ๎›พ๎žข๎Ž๎ฑ๎žช๎ถข๎žฟ๎ฑ๎ฏ๎žช๎ฏ๎ด’๎œฉ๎œข๎žฟ๎ด’๎žŸ๎œฉ
๎˜ง๎œฉ๎žŸ๎›พ๎žข๎žท๎›พ๎ฏ๎œฉ๎ฑ๎žท๎ป๎˜‚ ๎˜ƒ๎œ›๎›พ๎œข๎œช๎ฏ๎Ž๎œ›๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎™ฒ๎Ž๎œ›๎žข๎ป๎œš๎Ž๎ป๎ฆ๎ป๎‚๎๎›พ๎˜‚ ๎™ฒ๎œช๎œข๎Ž๎œ›๎›พ๎ดŒ๎˜‚ ๎™†๎›พ๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚
๎œข๎œฉ๎˜‚๎™ฒ๎œฉ๎œข๎Ž๎œ›๎Ž๎ฑ๎›พ๎ดŒ๎˜‚๎›ƒ๎ฑ๎Ž๎Ÿ›๎œฉ๎žข๎žช๎Ž๎œข๎›พ๎œข๎˜‚๎™ด๎›พ๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚๎™ฒ๎›พ๎Ÿข๎ป๎žข๎˜‚๎œข๎œฉ๎˜‚๎šฎ๎›พ๎ฑ๎˜‚๎™ฒ๎›พ๎žข๎œ›๎ป๎žช๎ด’๎˜‚๎™จ๎Ž๎ฏ๎›พ๎ดŒ๎˜‚
๎šฃ๎œฉ๎žข๎Ÿ€
๎˜ง๎™ฟ๎™“๎ด‹๎˜‚๎‰๎žท๎žท๎žŸ๎ด‹๎ด˜๎ด˜๎œข๎Ÿก๎ด’๎œข๎ป๎Ž๎ด’๎ป๎žข๎‚๎ด˜๎ฒš๎ฒ™๎ด’๎ฒ›๎ฒ๎ฒ™๎ฒœ๎ฒข๎ดž๎œ›๎Ÿ›๎ฒ›๎ฒ™๎ฒ›๎ฒ™๎ฒก๎ฒš๎ฒ ๎ฒž๎ฒก
๎šฆ๎ ฐ๎ ข๎ก—๎ ก๎ก—๎ ฉ๎ข…๎ด‹๎˜‚๎ „๎ ก๎ขฌ๎ก—๎กฐ๎˜‚๎ฒ‘๎ฒ—๎˜‚๎ ฉ๎ ฐ๎กฐ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎˜‚๎˜‚๎˜‚๎˜‚๎ถช๎˜‚๎˜‚๎˜‚๎˜‚๎šฆ๎ ฐ๎ฃค๎ก—๎ขด๎ „๎ ฉ๎ข…๎ด‹๎˜‚๎กน๎ „๎ฃซ๎ข…๎˜‚๎ฒ‘๎ฒ˜๎˜‚๎ ฉ๎ ฐ๎กฐ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎˜‚๎˜‚๎˜‚๎˜‚๎ถช๎˜‚๎˜‚๎˜‚๎˜‚๎˜ƒ๎ ข๎ ฐ๎ขฉ๎ฃ€๎ „๎ ฉ๎ข…๎ด‹๎˜‚๎กช๎ฃˆ๎กป๎ก—๎ข…๎˜‚๎ฒ๎ฒ๎˜‚๎ ฉ๎ ฐ๎กฐ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 | e- issn 2311-2212๎ฒ๎ฒ—
Introducciรณn
๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎ดฃ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ดค๎ด‹๎˜‚ ๎™จ๎ป๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎žช๎œฉ๎˜‚ ๎žช๎›พ๎œš๎œฉ๎˜‚ ๎Ÿข๎˜‚ ๎ฆ๎ป๎˜‚
๎žก๎žฟ๎œฉ๎˜‚๎žช๎œฉ๎˜‚๎œ›๎ป๎ฑ๎ป๎œ›๎œฉ
El 31 de diciembre de 2019, China reportรณ a la WHO
(World Health Organization) una neumonรญa atรญpica en la
ciudad de Wuhan, provincia de Hubei (WHO, 2020a).
El 12 de enero de 2020, China compartiรณ pรบblicamente
la secuencia genรฉtica del nuevo coronavirus 2019-
nCoV (WHO, 2020b). El 11 de febrero de 2020, la ICTV
(International Committee on Taxonomy of Viruses) anunciรณ
๎œฉ๎ฆ๎˜‚ ๎ฑ๎ป๎ฏ๎œš๎žข๎œฉ๎˜‚ ๎ป๎ €๎œ›๎Ž๎›พ๎ฆ๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎ฑ๎žฟ๎œฉ๎Ÿ›๎ป๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎ดŒ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎ดŒ๎˜‚
previamente dilucidado genรฉticamente (Gorbalenya,
et al., 2020, Zhou et al., 2020) y paralelamente la WHO
๎›พ๎ฑ๎žฟ๎ฑ๎œ›๎Ž๎ผ๎˜‚๎œฉ๎ฆ๎˜‚๎ฑ๎ป๎ฏ๎œš๎žข๎œฉ๎˜‚๎ป๎ €๎œ›๎Ž๎›พ๎ฆ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚๎œฉ๎ฑ๎๎œฉ๎žข๎ฏ๎œฉ๎œข๎›พ๎œข๎ดŒ๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚
(WHO, 2020c). El 13 de febrero, China reportรณ un
aumento de 15.152 casos respecto al dรญa anterior. Este
aumento se debiรณ al cambio del mรฉtodo de detecciรณn.
Inicialmente, los casos diagnosticados de la enfermedad
๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎žช๎œฉ๎˜‚ ๎žข๎œฉ๎›พ๎ฆ๎Ž๎Ÿฌ๎›พ๎œš๎›พ๎ฑ๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎œš๎›พ๎žช๎œฉ๎˜‚ ๎›พ๎˜‚ ๎žช๎Ž๎ฑ๎žท๎ป๎ฏ๎›พ๎žท๎ป๎ฆ๎ป๎‚๎๎›พ๎ดŒ๎˜‚
๎Ž๎ฏ๎›ฟ๎‚๎œฉ๎ฑ๎œฉ๎žช๎˜‚ ๎žท๎ป๎žข๎›ฟ๎œ›๎Ž๎œ›๎›พ๎žช๎˜‚๎Ÿข๎˜‚ ๎žช๎Ž๎‚๎ฑ๎ป๎žช๎˜‚ ๎œ›๎ฆ๎๎ฑ๎Ž๎œ›๎ป๎žช๎˜‚ ๎Ž๎œข๎œฉ๎ฑ๎žท๎Ž๎ €๎œ›๎›พ๎œš๎ฆ๎œฉ๎žช๎˜‚ ๎žŸ๎ป๎žข๎˜‚
un profesional mรฉdico capacitado, posteriormente, se
๎žข๎œฉ๎›พ๎ฆ๎Ž๎Ÿฌ๎›พ๎žข๎ป๎ฑ๎˜‚ ๎žŸ๎žข๎žฟ๎œฉ๎œš๎›พ๎žช๎˜‚ ๎œข๎œฉ๎˜‚ ๎œข๎œฉ๎žท๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚ ๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ
CoV2 (Situational Report Hubei Province, 2020), las
mismas que fueron mucho mรกs precisas en la detecciรณn
(Liu et al., 2020b; Yu et al๎ด’๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎˜ฏ๎ฆ๎˜‚ ๎ฒ๎ฒ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฏ๎›พ๎žข๎Ÿฌ๎ป๎ดŒ๎˜‚ ๎ฆ๎›พ๎˜‚
๎› ๎™Ž๎™ฟ๎˜‚ ๎œข๎œฉ๎œ›๎ฆ๎›พ๎žข๎ผ๎˜‚ ๎›พ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎œ›๎ผ๎ฏ๎ป๎˜‚ ๎žŸ๎›พ๎ฑ๎œข๎œฉ๎ฏ๎Ž๎›พ๎˜‚ ๎ดฃ๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚
๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎›พ๎ดค๎ด’๎˜‚ ๎˜ฏ๎ฆ๎˜‚ ๎ฒ๎ฒ•๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฏ๎›พ๎žข๎Ÿฌ๎ป๎ดŒ๎˜‚ ๎šฃ๎œฉ๎žข๎Ÿ€๎˜‚ ๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎ผ๎˜‚ ๎žช๎žฟ๎˜‚ ๎žŸ๎žข๎Ž๎ฏ๎œฉ๎žข๎˜‚ ๎œ›๎›พ๎žช๎ป๎˜‚
๎œข๎œฉ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎ดฃ๎šฃ๎žข๎œฉ๎žช๎Ž๎œข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎šฆ๎œฉ๎žŸ๎Ÿ€๎œš๎ฆ๎Ž๎œ›๎›พ๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎šฃ๎œฉ๎žข๎Ÿ€๎ดŒ๎˜‚
๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎˜ƒ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎ดฃ๎ฒ’๎ฒ๎˜‚ ๎œข๎œฉ๎˜‚ ๎›พ๎œš๎žข๎Ž๎ฆ๎ดค๎˜‚ ๎žช๎œฉ๎˜‚ ๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎›พ๎ฑ๎˜‚ ๎ฏ๎›ฟ๎žช๎˜‚ ๎œข๎œฉ๎˜‚
3,2 millones de casos y mรกs de 231 mil fallecidos en el
๎ฏ๎žฟ๎ฑ๎œข๎ป๎ดŒ๎˜‚๎œ›๎ป๎ฑ๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎ฏ๎ป๎žข๎žท๎›พ๎ฆ๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎ฒ–๎ด’๎ฒ๎ฒ๎ถ‡๎˜‚๎ดฃ๎˜ง๎ป๎ฑ๎‚๎˜‚et al., 2020),
๎Ÿข๎˜‚๎œ›๎›พ๎žช๎Ž๎˜‚๎ฒ’๎ฒ–๎˜‚๎ฏ๎Ž๎ฆ๎˜‚๎œ›๎›พ๎žช๎ป๎žช๎˜‚๎œ›๎ป๎ฑ๎˜‚๎ฏ๎›ฟ๎žช๎˜‚๎œข๎œฉ๎˜‚๎ฒ๎ฒ๎ฒ๎ฒ๎˜‚๎๎›พ๎ฆ๎ฆ๎œฉ๎œ›๎Ž๎œข๎ป๎žช๎˜‚๎œฉ๎ฑ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€๎ดŒ๎˜‚
๎œ›๎ป๎ฑ๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎ฏ๎ป๎žข๎žท๎›พ๎ฆ๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚ ๎ฒ‘๎ด’๎ฒ—๎ฒ“๎ถ‡๎˜‚ ๎ดฃ๎™ฒ๎Ž๎ฑ๎Ž๎žช๎žท๎œฉ๎žข๎Ž๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎›พ๎ฆ๎žฟ๎œข๎˜‚๎œข๎œฉ๎ฆ๎˜‚
๎šฃ๎œฉ๎žข๎Ÿ€๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚
La familia Coronaviridae comprende siete especies
que causan infecciones respiratorias: infecciones por
๎™Ž๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎ฒ‘๎ฒ˜๎˜ฏ๎ดŒ๎˜‚ ๎™ฟ๎˜ ๎ฒ“๎ฒ’๎ดŒ๎˜‚ ๎™ด๎™จ๎ฒ•๎ฒ’๎ดŒ๎˜‚ ๎Ÿข๎˜‚ ๎™Ž๎™ฆ๎›ƒ๎ฒ๎˜‚ ๎žช๎œฉ๎˜‚ ๎ฑ๎ป๎žท๎Ž๎ €๎œ›๎›พ๎ฑ๎˜‚ ๎œ›๎ป๎ฏ๎ป๎˜‚
๎ฏ๎ป๎œข๎œฉ๎žข๎›พ๎œข๎›พ๎žช๎ด—๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎˜‚ ๎ดฃ๎žก๎žฟ๎œฉ๎˜‚ ๎œ›๎›พ๎žฟ๎žช๎›พ๎˜‚ ๎šฎ๎๎ฑ๎œข๎žข๎ป๎ฏ๎œฉ๎˜‚ ๎šฆ๎œฉ๎žช๎žŸ๎Ž๎žข๎›พ๎žท๎ป๎žข๎Ž๎ป๎˜‚
๎˜ƒ๎‚๎žฟ๎œข๎ป๎˜‚๎šฎ๎œฉ๎Ÿ›๎œฉ๎žข๎ป๎ดค๎ดŒ๎˜‚๎™ฒ๎˜ฏ๎šฆ๎šฎ๎˜‚๎ดฃ๎šฎ๎๎ฑ๎œข๎žข๎ป๎ฏ๎œฉ๎˜‚๎šฆ๎œฉ๎žช๎žŸ๎Ž๎žข๎›พ๎žท๎ป๎žข๎Ž๎ป๎˜‚๎œข๎œฉ๎ฆ๎˜‚๎™ฒ๎œฉ๎œข๎Ž๎ป๎˜‚
๎™ฟ๎žข๎Ž๎œฉ๎ฑ๎žท๎œฉ๎ดค๎˜‚ ๎Ÿข๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎ดฃ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ดค๎˜‚ ๎žช๎ป๎ฑ๎˜‚ ๎œ›๎ป๎ฑ๎žช๎Ž๎œข๎œฉ๎žข๎›พ๎œข๎ป๎žช๎˜‚
๎‚๎žข๎›พ๎Ÿ›๎œฉ๎žช๎˜‚ ๎ดฃ๎™Ž๎žฟ๎›พ๎ฑ๎‚๎˜‚ ๎œฉ๎žท๎˜‚ ๎›พ๎ฆ๎ด’๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด—๎˜‚ ๎šฎ๎ป๎ฑ๎‚๎˜‚ et al., 2019). Los
๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎žŸ๎ป๎žช๎œฉ๎œฉ๎ฑ๎˜‚๎žฟ๎ฑ๎˜‚๎‚๎œฉ๎ฑ๎ป๎ฏ๎›พ๎˜‚๎šฆ๎™ด๎˜ƒ๎˜‚๎žช๎žช๎ตฏ๎˜‚๎ดฃ๎˜ƒ๎šฆ๎™ด๎˜‚๎œข๎œฉ๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎žช๎ป๎ฆ๎›พ๎˜‚
cadena de sentido positivo) cuyo tamaรฑo varรญa de 27 a 32
๎ฃ๎œš๎ด’๎˜‚๎›ƒ๎ฑ๎˜‚๎žท๎œฉ๎žข๎œ›๎Ž๎ป๎˜‚๎œข๎œฉ๎˜‚๎žช๎žฟ๎˜‚๎˜ƒ๎šฆ๎™ด๎˜‚๎œ›๎ป๎œข๎Ž๎ €๎œ›๎›พ๎˜‚๎žŸ๎žข๎ป๎žท๎œฉ๎๎ฑ๎›พ๎žช๎˜‚๎œฉ๎žช๎žท๎žข๎žฟ๎œ›๎žท๎žฟ๎žข๎›พ๎ฆ๎œฉ๎žช๎˜‚
๎œ›๎ป๎ฏ๎ป๎˜‚๎ฆ๎›พ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚๎œฉ๎žช๎žŸ๎๎œ›๎žฟ๎ฆ๎›พ๎˜‚๎ดฃ๎šฎ๎ดค๎ดŒ๎˜‚๎Ÿข๎˜‚๎žŸ๎žข๎ป๎žท๎œฉ๎๎ฑ๎›พ๎žช๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚๎œฉ๎ฑ๎Ÿ›๎ป๎ฆ๎žท๎žฟ๎žข๎›พ๎˜‚๎ดฃ๎˜ฏ๎ดค๎ดŒ๎˜‚
la membrana (M) y la nucleocรกpside (N). Los otros dos
๎žท๎œฉ๎žข๎œ›๎Ž๎ป๎žช๎˜‚๎œข๎œฉ๎ฆ๎˜‚๎‚๎œฉ๎ฑ๎ป๎ฏ๎›พ๎˜‚๎œ›๎ป๎œข๎Ž๎ €๎œ›๎›พ๎ฑ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎žŸ๎ป๎ฆ๎Ž๎žŸ๎žข๎ป๎žท๎œฉ๎๎ฑ๎›พ๎žช๎˜‚๎™ฟ๎šฆ๎™†๎ฒ๎›พ๎˜‚๎Ÿข๎˜‚
๎™ฟ๎šฆ๎™†๎ฒ๎œš๎ดŒ๎˜‚ ๎Ÿข๎˜‚ ๎ป๎žท๎žข๎›พ๎žช๎˜‚ ๎žŸ๎žข๎ป๎žท๎œฉ๎๎ฑ๎›พ๎žช๎˜‚ ๎ฑ๎ป๎˜‚ ๎œฉ๎žช๎žท๎žข๎žฟ๎œ›๎žท๎žฟ๎žข๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎Ž๎ฏ๎žŸ๎ฆ๎Ž๎œ›๎›พ๎œข๎›พ๎žช๎˜‚
๎œฉ๎ฑ๎˜‚๎ฆ๎›พ๎˜‚๎žช๎๎ฑ๎žท๎œฉ๎žช๎Ž๎žช๎˜‚๎œข๎œฉ๎˜‚๎˜ƒ๎šฆ๎™ด๎˜‚๎ดฃ๎™†๎›พ๎ฑ et al๎ด’๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚๎šฎ๎œฉ๎‚๎Ÿ€๎ฑ๎˜‚๎ฆ๎›พ๎˜‚๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚
๎›พ๎˜‚๎ฑ๎Ž๎Ÿ›๎œฉ๎ฆ๎˜‚๎‚๎ฆ๎ป๎œš๎›พ๎ฆ๎˜‚๎ฆ๎›พ๎˜‚๎žท๎›พ๎žช๎›พ๎˜‚๎œข๎œฉ๎˜‚๎ฏ๎ป๎žข๎žท๎›พ๎ฆ๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎˜‚๎œฉ๎žช๎˜‚๎œข๎œฉ๎˜‚๎ฒ๎ฒ“๎˜‚๎›พ๎˜‚
๎ฒ๎ฒ”๎ถ‡๎˜‚๎ดฃ๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ”๎ดค๎ดŒ๎˜‚๎œข๎œฉ๎˜‚๎™ฒ๎˜ฏ๎šฆ๎šฎ๎˜‚๎œฉ๎žช๎˜‚๎œข๎œฉ๎˜‚๎ฒ’๎ฒ“๎ด’๎ฒ“๎ถ‡๎˜‚๎ดฃ๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎œข๎ดค๎ดŒ๎˜‚๎Ÿข๎˜‚
๎œข๎œฉ๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚๎œข๎œฉ๎˜‚๎ฒ’๎ถ‡๎˜‚๎›พ๎˜‚๎ฒ“๎ถ‡๎˜‚๎ดฃ๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎œฉ๎ดค๎ด’๎˜‚๎˜ƒ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎ฆ๎›พ๎˜‚
๎œ›๎ป๎ฑ๎žท๎›พ๎‚๎Ž๎ป๎žช๎Ž๎œข๎›พ๎œข๎˜‚๎ดฃ๎šฆ๎ฒ๎ดค๎˜‚๎œข๎œฉ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎œฉ๎ฑ๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎๎›พ๎žช๎œฉ๎˜‚๎œข๎œฉ๎˜‚๎œš๎žข๎ป๎žท๎œฉ๎˜‚
se ha estimado entre 2.2 โ€“ 3.6 (Zhao et al, 2020).
Los estudios epidemiolรณgicos sobre coronavirus
datan de muchos aรฑos, demostrรกndose que los
murciรฉlagos son los principales agentes de transmisiรณn
y diseminaciรณn de estos patรณgenos (Cui et al., 2019;
๎™†๎›พ๎ฑ๎˜‚ et al., 2019; Wong et al., 2019). Evidencia reciente
๎žŸ๎ป๎ฑ๎œฉ๎˜‚๎œข๎œฉ๎˜‚๎ฏ๎›พ๎ฑ๎Ž๎ €๎œฉ๎žช๎žท๎ป๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎ฆ๎ป๎žช๎˜‚๎žŸ๎›พ๎ฑ๎‚๎ป๎ฆ๎Ž๎ฑ๎œฉ๎žช๎˜‚๎žŸ๎ป๎œข๎žข๎๎›พ๎ฑ๎˜‚๎žช๎œฉ๎žข๎˜‚๎ฆ๎ป๎žช๎˜‚
reservorios intermedios de coronavirus y esto aumenta la
๎žŸ๎ป๎žช๎Ž๎œš๎Ž๎ฆ๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎œ›๎›พ๎žฟ๎žช๎›พ๎žข๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎ฏ๎›พ๎Ÿข๎ป๎žข๎˜‚๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎˜‚๎Ÿฌ๎ป๎ป๎ฑ๎ผ๎žท๎Ž๎œ›๎›พ๎˜‚
y generar nuevos brotes (Lam et al.๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎šฃ๎ป๎žข๎˜‚ ๎žฟ๎ฑ๎˜‚
lado, algunos estudios demuestran que la velocidad de
๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎ฆ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎œฉ๎žช๎˜‚๎œข๎œฉ๎œš๎Ž๎œข๎ป๎˜‚๎›พ๎˜‚๎ฏ๎ป๎œข๎Ž๎ €๎œ›๎›พ๎œ›๎Ž๎ป๎ฑ๎œฉ๎žช๎˜‚
๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎žŸ๎žข๎ป๎žท๎œฉ๎๎ฑ๎›พ๎˜‚ ๎šฎ๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎žข๎œฉ๎‚๎Ž๎ผ๎ฑ๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎œข๎ป๎ฏ๎Ž๎ฑ๎Ž๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎žฟ๎ฑ๎Ž๎ผ๎ฑ๎˜‚ ๎›พ๎ฆ๎˜‚
๎žข๎œฉ๎œ›๎œฉ๎žŸ๎žท๎ป๎žข๎˜‚๎ดฃ๎šฆ๎˜Ÿ๎˜ง๎ดค๎ดŒ๎˜‚๎ฆ๎›พ๎˜‚๎œ›๎žฟ๎›พ๎ฆ๎˜‚๎žช๎œฉ๎˜‚๎žฟ๎ฑ๎œฉ๎˜‚๎›พ๎ฆ๎˜‚๎žข๎œฉ๎œ›๎œฉ๎žŸ๎žท๎ป๎žข๎˜‚๎˜ƒ๎˜ ๎˜ฏ๎ฒ‘๎˜‚๎‰๎žฟ๎ฏ๎›พ๎ฑ๎ป๎˜‚
๎ดฃ๎‰๎˜ƒ๎˜ ๎˜ฏ๎ฒ‘๎ดค๎˜‚ ๎ดฃ๎™Ž๎ป๎Ÿฒ๎๎ฏ๎›พ๎ฑ๎ฑ๎˜‚ et al๎ด’๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎˜ง๎Ž๎œ›๎‰๎›พ๎˜‚ ๎œ›๎›พ๎žŸ๎›พ๎œ›๎Ž๎œข๎›พ๎œข๎˜‚ ๎œข๎œฉ๎˜‚
๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎˜‚ ๎œฉ๎žช๎˜‚ ๎Ž๎ฑ๎œ›๎ฆ๎žฟ๎žช๎ป๎˜‚ ๎ฏ๎œฉ๎ ๎ป๎žข๎˜‚ ๎Ÿข๎˜‚ ๎ฏ๎›พ๎Ÿข๎ป๎žข๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดŒ๎˜‚
๎ฆ๎ป๎˜‚ ๎œ›๎žฟ๎›พ๎ฆ๎˜‚ ๎žŸ๎ป๎ฑ๎œฉ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฏ๎›พ๎ฑ๎Ž๎ €๎œฉ๎žช๎žท๎ป๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎žŸ๎ป๎œข๎žข๎๎›พ๎˜‚ ๎žช๎œฉ๎žข๎˜‚
un producto de un evento natural de mejoramiento por
recombinaciรณn genรฉtica en uno o en varios reservorios
๎ฑ๎›พ๎žท๎žฟ๎žข๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎ดฃ๎šฎ๎‰๎œฉ๎žข๎œฉ๎œฉ๎ฑ๎˜‚ et al.๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎šฃ๎ป๎žข๎˜‚ ๎ป๎žท๎žข๎ป๎˜‚ ๎ฆ๎›พ๎œข๎ป๎ดŒ๎˜‚ ๎ป๎žท๎žข๎ป๎žช๎˜‚
estudios muestran que la capacidad de transmisiรณn de
๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎œฉ๎žช๎˜‚๎žท๎›พ๎ฆ๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎žช๎œฉ๎˜‚๎œ›๎ป๎ฑ๎žท๎›พ๎‚๎Ž๎›พ๎˜‚๎Ÿข๎˜‚๎žŸ๎žข๎ป๎žŸ๎›พ๎‚๎›พ๎˜‚๎žข๎›ฟ๎žŸ๎Ž๎œข๎›พ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚
incluso de persona a persona en hogares; eso implica
que es importante aislar rรกpidamente a los pacientes
sintomรกticos, rastrear y poner en aislamiento a todos
sus contactos (pacientes asintomรกticos) a la brevedad
posible (Chan et al., 2020).
Los coronavirus inician su replicaciรณn viral en el
tracto respiratorio superior, y con frecuencia infectan
las vรญas respiratorias terminales, causando interrupciรณn
del intercambio gaseoso y resultando posteriormente
en una necrosis de las cรฉlulas alveolares. En una
primera etapa de la infecciรณn, los sรญntomas comunes
๎žช๎ป๎ฑ๎˜‚๎ €๎œฉ๎œš๎žข๎œฉ๎˜‚๎œฉ๎žช๎œ›๎›พ๎ฆ๎ป๎๎žข๎๎ป๎žช๎ดŒ๎˜‚๎žท๎ป๎žช๎˜‚๎žช๎œฉ๎œ›๎›พ๎ดŒ๎˜‚๎Ÿข๎˜‚๎œข๎Ž๎žช๎ฑ๎œฉ๎›พ๎ด—๎˜‚๎ฏ๎Ž๎œฉ๎ฑ๎žท๎žข๎›พ๎žช๎˜‚๎žก๎žฟ๎œฉ๎˜‚
๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎žฟ๎ฑ๎›พ๎˜‚ ๎œฉ๎žท๎›พ๎žŸ๎›พ๎˜‚ ๎›พ๎Ÿ›๎›พ๎ฑ๎Ÿฌ๎›พ๎œข๎›พ๎˜‚ ๎ฆ๎›พ๎žช๎˜‚ ๎œ›๎ป๎ฏ๎žŸ๎ฆ๎Ž๎œ›๎›พ๎œ›๎Ž๎ป๎ฑ๎œฉ๎žช๎˜‚ ๎œ›๎ฆ๎๎ฑ๎Ž๎œ›๎›พ๎žช๎˜‚
๎žช๎ป๎ฑ๎˜‚ ๎ฑ๎œฉ๎žฟ๎ฏ๎ป๎ฑ๎๎›พ๎˜‚ ๎žข๎›ฟ๎žŸ๎Ž๎œข๎›พ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚ ๎žŸ๎žข๎ป๎‚๎žข๎œฉ๎žช๎Ž๎Ÿ›๎›พ๎ดŒ๎˜‚ ๎œข๎Ž๎ €๎œ›๎žฟ๎ฆ๎žท๎›พ๎œข๎˜‚
๎žข๎œฉ๎žช๎žŸ๎Ž๎žข๎›พ๎žท๎ป๎žข๎Ž๎›พ๎˜‚๎›พ๎‚๎žฟ๎œข๎›พ๎˜‚ ๎‚๎žข๎›พ๎Ÿ›๎œฉ๎˜‚ ๎ดฃ๎˜ƒ๎šฆ๎˜ง๎šฎ๎ดค๎ดŒ๎˜‚ ๎œข๎›พ๎บ๎ป๎˜‚ ๎›พ๎ฆ๎Ÿ›๎œฉ๎ป๎ฆ๎›พ๎žข๎˜‚ ๎œข๎Ž๎๎žฟ๎žช๎ป๎˜‚
๎ดฃ๎˜ง๎˜ƒ๎˜ง๎ดค๎ดŒ๎˜‚ ๎Ž๎ฑ๎žช๎žฟ๎ €๎œ›๎Ž๎œฉ๎ฑ๎œ›๎Ž๎›พ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎Ž๎žข๎›พ๎žท๎ป๎žข๎Ž๎›พ๎ดŒ๎˜‚ ๎Ÿข๎˜‚ ๎ €๎œš๎žข๎ป๎žช๎Ž๎žช๎˜‚ ๎ดฃ๎™ด๎œฉ๎Ÿœ๎žท๎ป๎ฑ๎˜‚
et al., 2016). Los mecanismos inmunolรณgicos de
respuesta frente a una infecciรณn viral se basan en el
reconocimiento de patrones moleculares asociados a
๎žŸ๎›พ๎žท๎ผ๎‚๎œฉ๎ฑ๎ป๎žช๎˜‚๎ดฃ๎šฃ๎˜ƒ๎™ฒ๎šฃ๎ดค๎˜‚๎žŸ๎ป๎žข๎˜‚๎ฆ๎ป๎žช๎˜‚๎žข๎œฉ๎œ›๎œฉ๎žŸ๎žท๎ป๎žข๎œฉ๎žช๎˜‚๎œข๎œฉ๎˜‚๎žข๎œฉ๎œ›๎ป๎ฑ๎ป๎œ›๎Ž๎ฏ๎Ž๎œฉ๎ฑ๎žท๎ป๎˜‚
๎œข๎œฉ๎˜‚๎žŸ๎›พ๎žท๎žข๎ป๎ฑ๎œฉ๎žช๎˜‚๎ดฃ๎šฃ๎šฆ๎šฆ๎ดค๎˜‚๎žฟ๎œš๎Ž๎œ›๎›พ๎œข๎ป๎žช๎˜‚๎œฉ๎ฑ๎˜‚๎œ›๎›พ๎žช๎Ž๎˜‚๎žท๎ป๎œข๎›พ๎žช๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎œข๎œฉ๎ฆ๎˜‚
๎œ›๎žฟ๎œฉ๎žข๎žŸ๎ป๎˜‚๎ดฃ๎™ด๎œฉ๎Ÿœ๎žท๎ป๎ฑ๎˜‚et al., 2016). La primera respuesta frente
a una infecciรณn viral es la producciรณn de interferones
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 |e- issn 2311-2212 19
๎ดฃ๎™“๎™†๎™ด๎ดค๎ดŒ๎˜‚ ๎œฉ๎žช๎œฉ๎ฑ๎œ›๎Ž๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚ ๎™“๎™†๎™ด๎˜‚ ๎œข๎œฉ๎˜‚ ๎žท๎Ž๎žŸ๎ป๎˜‚ ๎™“๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎Ž๎ฑ๎œข๎žฟ๎œ›๎Ž๎žข๎˜‚ ๎ฆ๎›พ๎˜‚
expresiรณn de molรฉculas (citoquinas) que activan
๎œข๎Ž๎žข๎œฉ๎œ›๎žท๎›พ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚ ๎›พ๎˜‚ ๎ฆ๎›พ๎žช๎˜‚ ๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎žช๎Ž๎žช๎žท๎œฉ๎ฏ๎›พ๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎œฉ๎ด’๎˜‚ ๎˜ƒ๎žช๎๎ดŒ๎˜‚ ๎ฆ๎›พ๎˜‚
activaciรณn de macrรณfagos, la maduraciรณn de las cรฉlulas
dendrรญticas, la activaciรณn y diferenciaciรณn de las cรฉlulas
T, la proliferaciรณn y expansiรณn clonal de las cรฉlulas T, y
๎ฆ๎›พ๎˜‚๎œข๎Ž๎๎œฉ๎žข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎˜Ÿ๎˜‚๎œฉ๎ฑ๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎žŸ๎ฆ๎›พ๎žช๎ฏ๎›ฟ๎žท๎Ž๎œ›๎›พ๎žช๎˜‚
para la producciรณn de anticuerpos, entre otras, son la
consecuencia de la activaciรณn de la respuesta inmune
๎ฏ๎œฉ๎œข๎Ž๎›พ๎œข๎›พ๎˜‚๎žŸ๎ป๎žข๎˜‚๎ฆ๎ป๎žช๎˜‚๎™“๎™†๎™ด๎˜‚๎ดฃ๎™†๎Ž๎‚๎žฟ๎žข๎›พ๎˜‚๎ฒ๎ดค๎ด’๎˜‚๎˜ƒ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎žช๎œฉ๎˜‚๎œ›๎ป๎ฑ๎ป๎œ›๎œฉ๎˜‚
๎žก๎žฟ๎œฉ๎˜‚๎ป๎žท๎žข๎›พ๎˜‚๎๎›พ๎ฏ๎Ž๎ฆ๎Ž๎›พ๎˜‚๎œข๎œฉ๎˜‚๎™“๎™†๎™ด๎ดŒ๎˜‚๎™“๎™†๎™ด๎˜‚๎œข๎œฉ๎˜‚๎žท๎Ž๎žŸ๎ป๎˜‚๎ฒ’๎ดŒ๎˜‚๎œ›๎žฟ๎Ÿข๎›พ๎˜‚๎žŸ๎žข๎ป๎œข๎žฟ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚
es mediada por las cรฉlulas epiteliales pulmonares,
๎œ›๎ป๎ฏ๎žŸ๎›พ๎žข๎žท๎œฉ๎ฑ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎Ÿ›๎๎›พ๎˜‚ ๎œข๎œฉ๎˜‚ ๎žช๎œฉ๎บ๎›พ๎ฆ๎Ž๎Ÿฌ๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚ ๎œ›๎ป๎ฑ๎˜‚ ๎™“๎™†๎™ด๎˜‚ ๎œข๎œฉ๎˜‚ ๎žท๎Ž๎žŸ๎ป๎˜‚ ๎™“๎˜‚ ๎ฆ๎ป๎˜‚
cual indicarรญa que coinciden en actividades biolรณgicas
๎›พ๎ฑ๎žท๎Ž๎Ÿ›๎Ž๎žข๎›พ๎ฆ๎œฉ๎žช๎˜‚๎ดฃ๎™ฒ๎›พ๎žข๎๎ฑ๎ดฎ๎šฎ๎›ฟ๎ฑ๎œ›๎‰๎œฉ๎Ÿฌ๎˜‚et al., 2020).
๎˜ƒ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎žช๎ป๎ฆ๎ป๎˜‚ ๎žช๎œฉ๎˜‚ ๎œ›๎ป๎ฑ๎ป๎œ›๎œฉ๎˜‚ ๎žฟ๎ฑ๎˜‚ ๎ฏ๎ป๎œข๎œฉ๎ฆ๎ป๎˜‚ ๎œข๎œฉ๎˜‚
inmunidad, lo cual sugiere que los murciรฉlagos secretan
๎œ›๎ป๎ฑ๎žช๎žท๎Ž๎žท๎žฟ๎žท๎Ž๎Ÿ›๎›พ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚ ๎™“๎™†๎™ด๎˜‚ ๎œข๎œฉ๎˜‚ ๎žท๎Ž๎žŸ๎ป๎˜‚ ๎ฒ๎˜‚ ๎ดฃ๎™“๎™†๎™ด๎ดฎ๎ซš๎ดค๎ดŒ๎˜‚ ๎Ÿข๎˜‚ ๎œฉ๎žช๎žท๎ป๎˜‚ ๎ฆ๎œฉ๎žช๎˜‚
๎žŸ๎žข๎ป๎žท๎œฉ๎‚๎œฉ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚๎Ž๎ฑ๎๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚๎ดฃ๎™†๎›พ๎ฑ๎˜‚et al., 2019). Las infecciones
con coronavirus presentan una caracterรญstica particular,
la ausencia de una fuerte respuesta antiviral de
cรฉlulas T al contravenir la respuesta efectora de las
๎žช๎žฟ๎œš๎žŸ๎ป๎œš๎ฆ๎›พ๎œ›๎Ž๎ป๎ฑ๎œฉ๎žช๎˜‚๎ ƒ๎ฒ๎˜‚๎Ÿข๎˜‚๎ ƒ๎ฒ‘๎˜‚๎ฆ๎ป๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎Ž๎ฑ๎œ›๎žข๎œฉ๎ฏ๎œฉ๎ฑ๎žท๎›พ๎˜‚๎ฆ๎›พ๎˜‚๎žช๎œฉ๎œ›๎žข๎œฉ๎œ›๎Ž๎ผ๎ฑ๎˜‚
๎œข๎œฉ๎˜‚๎œ›๎Ž๎žท๎ป๎žก๎žฟ๎Ž๎ฑ๎›พ๎žช๎˜‚๎žŸ๎žข๎ป๎Ž๎ฑ๎Ÿด๎ฆ๎›พ๎ฏ๎›พ๎žท๎ป๎žข๎Ž๎›พ๎žช๎˜‚๎ดฃ๎žท๎ป๎žข๎ฏ๎œฉ๎ฑ๎žท๎›พ๎˜‚๎œข๎œฉ๎˜‚๎œ›๎Ž๎žท๎ป๎žก๎žฟ๎Ž๎ฑ๎›พ๎žช๎ดค๎˜‚
๎๎›พ๎Ÿ›๎ป๎žข๎œฉ๎œ›๎Ž๎œฉ๎ฑ๎œข๎ป๎˜‚๎ฆ๎›พ๎˜‚๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎ป๎žŸ๎›พ๎žท๎ป๎ฆ๎ป๎‚๎๎›พ๎˜‚๎ดฃ๎˜ƒ๎ฆ๎ป๎žช๎›พ๎Ž๎ฏ๎Ž et al., 2020;
Channappanavar et al., 2019).
El rรกpido secuenciamiento y posterior liberaciรณn
๎œข๎œฉ๎ฆ๎˜‚ ๎‚๎œฉ๎ฑ๎ป๎ฏ๎›พ๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎ดฃ๎› ๎™Ž๎™ฟ๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎œš๎ดค๎˜‚ ๎๎›พ๎Ÿ›๎ป๎žข๎œฉ๎œ›๎Ž๎ผ๎˜‚๎œฉ๎ฆ๎˜‚
desarrollo de mรฉtodos de diagnรณstico molecular por
๎žข๎šฆ๎šผ๎ดฎ๎šฃ๎˜ ๎šฆ๎˜‚๎ดฃReal-Time Reverse Transcription-Polymerase Chain
Reaction) (Corman et al๎ด’๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ƒ๎œข๎Ž๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎œ›๎ป๎ฑ๎˜‚ ๎œฉ๎ฆ๎˜‚
avance de la pandemia se han desarrollado pruebas para
๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎œข๎œฉ๎ฑ๎ป๎ฏ๎Ž๎ฑ๎›พ๎œข๎›พ๎žช๎˜‚ ๎žข๎›ฟ๎žŸ๎Ž๎œข๎›พ๎žช๎˜‚ ๎ดฃ๎žช๎œฉ๎žข๎ป๎ฆ๎ผ๎‚๎Ž๎œ›๎›พ๎žช๎ดค๎˜‚ ๎œš๎›พ๎žช๎›พ๎œข๎›พ๎žช๎˜‚
en la respuesta inmune y por consiguiente producciรณn
๎œข๎œฉ๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎ป๎‚๎ฆ๎ป๎œš๎žฟ๎ฆ๎Ž๎ฑ๎›พ๎žช๎˜‚ ๎ดฃ๎™“๎‚๎™ฒ๎ด˜๎™“๎‚๎™‡๎ดค๎˜‚ ๎œ›๎ป๎ฑ๎žท๎žข๎›พ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎ดฃ๎™จ๎Ž๎˜‚
et al๎ด’๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด—๎˜‚๎˜ƒ๎‰๎ฏ๎œฉ๎œข๎˜‚et al.๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎šฃ๎ป๎žข๎˜‚๎ป๎žท๎žข๎ป๎˜‚๎ฆ๎›พ๎œข๎ป๎ดŒ๎˜‚๎‰๎›พ๎Ÿข๎˜‚๎žŸ๎ป๎œ›๎ป๎žช๎˜‚
datos disponibles sobre la inmunidad desarrollada
๎๎žข๎œฉ๎ฑ๎žท๎œฉ๎˜‚๎›พ๎ฆ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎ด’๎˜‚๎˜ƒ๎œข๎Ž๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎‰๎›พ๎Ÿข๎˜‚๎ฏ๎›ฟ๎žช๎˜‚๎œข๎œฉ๎˜‚๎ฒ’๎ฒ—๎ฒ๎˜‚
๎œฉ๎ฑ๎žช๎›พ๎Ÿข๎ป๎žช๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎‰๎›พ๎ฑ๎˜‚ ๎žช๎Ž๎œข๎ป๎˜‚ ๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎›พ๎œข๎ป๎žช๎˜‚ ๎œฉ๎ฑ๎˜‚
๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎šผ๎žข๎Ž๎›พ๎ฆ๎žช๎ด’๎‚๎ป๎Ÿ›๎ด’๎˜‚๎˜ง๎Ž๎œ›๎‰๎ป๎žช๎˜‚๎œฉ๎ฑ๎žช๎›พ๎Ÿข๎ป๎žช๎˜‚๎Ÿ›๎›พ๎ฑ๎˜‚๎œข๎œฉ๎žช๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚๎œš๎Ÿ€๎žช๎žก๎žฟ๎œฉ๎œข๎›พ๎˜‚
de antivirales hasta tรฉcnicas de diagnรณstico por
imรกgenes. Los enfoques terapรฉuticos incluyen el plasma
de personas convalecientes, anticuerpos monoclonales
๎‰๎žฟ๎ฏ๎›พ๎ฑ๎Ž๎Ÿฌ๎›พ๎œข๎ป๎žช๎˜‚ ๎ฑ๎œฉ๎žฟ๎žท๎žข๎›พ๎ฆ๎Ž๎Ÿฌ๎›พ๎ฑ๎žท๎œฉ๎žช๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎žฟ๎žช๎ป๎˜‚ ๎žท๎œฉ๎žข๎›พ๎žŸ๎œช๎žฟ๎žท๎Ž๎œ›๎ป๎˜‚ ๎Ÿข๎˜‚
๎žŸ๎žข๎ป๎ €๎ฆ๎›ฟ๎œ›๎žท๎Ž๎œ›๎ป๎˜‚๎ดฃ๎˜ ๎›พ๎žข๎Ÿ›๎›พ๎ฆ๎‰๎ป๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด—๎˜‚๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎šผ๎žข๎Ž๎›พ๎ฆ๎žช๎ด’๎‚๎ป๎Ÿ›๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’
๎™†๎Ž๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎œฉ๎ฑ๎˜‚ ๎œฉ๎ฆ๎˜‚ ๎ฏ๎žฟ๎ฑ๎œข๎ป๎˜‚ ๎žช๎œฉ๎˜‚ ๎Ÿ›๎Ž๎œฉ๎ฑ๎œฉ๎ฑ๎˜‚ ๎œข๎œฉ๎žช๎›พ๎žข๎žข๎ป๎ฆ๎ฆ๎›พ๎ฑ๎œข๎ป๎˜‚
๎œ›๎›พ๎ฑ๎œข๎Ž๎œข๎›พ๎žท๎ป๎žช๎˜‚ ๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎œ›๎ป๎ฑ๎žท๎žข๎›พ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚ ๎ดฃ๎˜ ๎‰๎œฉ๎ฑ๎˜‚ et al.
2020; Liu et al๎ด’๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎›พ๎ดค๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎›พ๎žช๎๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎Ž๎Ÿฌ๎›พ๎žข๎˜‚ ๎Ÿข๎˜‚ ๎žŸ๎žข๎ป๎žท๎œฉ๎‚๎œฉ๎žข๎˜‚
๎œฉ๎ €๎œ›๎›พ๎Ÿฌ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚ ๎›พ๎˜‚ ๎ฆ๎›พ๎žช๎˜‚ ๎žŸ๎œฉ๎žข๎žช๎ป๎ฑ๎›พ๎žช๎˜‚ ๎œ›๎ป๎ฑ๎žท๎žข๎›พ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ด’๎˜‚ ๎™จ๎ป๎žช๎˜‚
๎œฉ๎žช๎๎žฟ๎œฉ๎žข๎Ÿฌ๎ป๎žช๎˜‚ ๎žช๎ป๎ฑ๎˜‚ ๎ฏ๎žฟ๎œ›๎‰๎ป๎žช๎ดŒ๎˜‚ ๎‰๎›พ๎œ›๎Ž๎œฉ๎ฑ๎œข๎ป๎˜‚ ๎žก๎žฟ๎œฉ๎˜‚ ๎›พ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎˜‚
se registren 89 candidatos a vacunas (WHO, 2020f).
๎˜ƒ๎œ›๎žท๎žฟ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎›พ๎ฆ๎˜‚๎ฒ’๎ฒ๎˜‚๎œข๎œฉ๎˜‚๎›พ๎œš๎žข๎Ž๎ฆ๎ดŒ๎˜‚๎‰๎›พ๎Ÿข๎˜‚๎ป๎œ›๎‰๎ป๎˜‚๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎žช๎˜‚๎ดฃ๎šผ๎›พ๎œš๎ฆ๎›พ๎˜‚๎ฒ๎ดค๎˜‚
que han superado las pruebas preclรญnicas, de las cuales
๎‰๎›พ๎Ÿข๎˜‚๎žฟ๎ฑ๎›พ๎˜‚๎œฉ๎ฑ๎˜‚๎๎›พ๎žช๎œฉ๎˜‚๎™“๎™“๎ด‹๎˜‚๎˜ƒ๎œข๎ฒ”๎ดฎ๎ฑ๎˜ ๎ป๎›Ÿ๎ดŒ๎˜‚๎žท๎žข๎œฉ๎žช๎˜‚๎œฉ๎ฑ๎˜‚๎๎›พ๎žช๎œฉ๎˜‚๎™“๎ดฎ๎™“๎™“๎˜‚๎žช๎Ž๎ฏ๎žฟ๎ฆ๎žท๎›ฟ๎ฑ๎œฉ๎›พ๎ด‹๎˜‚
๎™จ๎›Ÿ๎ดฎ๎šฎ๎™ฒ๎˜ฏ๎™ด๎šฃ๎ดฎ๎˜ง๎˜ ๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎˜‚ ๎ฑ๎˜ ๎ป๎›Ÿ๎˜‚ ๎›Ÿ๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚ ๎ดฃ๎™“๎ฑ๎›พ๎œ›๎žท๎Ž๎Ÿ›๎›พ๎žท๎œฉ๎œข๎ดค๎ดŒ๎˜‚ ๎Ÿข๎˜‚
๎˜ ๎‰๎˜ƒ๎œข๎™ฟ๎Ÿก๎ฒ๎ดŒ๎˜‚๎œ›๎žฟ๎›พ๎žท๎žข๎ป๎˜‚๎œฉ๎ฑ๎˜‚๎๎›พ๎žช๎œฉ๎˜‚๎™“๎ด‹๎˜‚๎›พ๎˜ƒ๎šฃ๎˜ ๎˜‚๎œฉ๎žช๎žŸ๎œฉ๎œ›๎๎ €๎œ›๎ป๎˜‚๎œข๎œฉ๎ฆ๎˜‚๎žŸ๎›พ๎žท๎ผ๎‚๎œฉ๎ฑ๎ป๎ดŒ๎˜‚
๎œš๎›พ๎œ›๎šผ๎šฆ๎™จ๎ดฎ๎šฎ๎žŸ๎Ž๎ฃ๎œฉ๎ดŒ๎˜‚๎™“๎™ด๎™ฟ๎ดฎ๎ฒ“๎ฒ—๎ฒ๎ฒ๎ดŒ๎˜‚๎Ÿข๎˜‚๎ฏ๎šฆ๎™ด๎˜ƒ๎ดฎ๎ฒ๎ฒ‘๎ฒ–๎ฒ’๎˜‚๎ดฃ๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎šผ๎žข๎Ž๎›พ๎ฆ๎žช๎ด’
๎‚๎ป๎Ÿ›๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด’๎ด—๎˜‚๎ ƒ๎›พ๎ฑ๎‰๎˜‚๎™จ๎œฉ๎˜‚et al., 2020).
Figura 1๎ด’๎˜‚๎šฆ๎œฉ๎žŸ๎žข๎œฉ๎žช๎œฉ๎ฑ๎žท๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎ป๎žข๎Ž๎‚๎œฉ๎ฑ๎ดŒ๎˜‚ ๎œ›๎ป๎ฑ๎žท๎›พ๎‚๎Ž๎ป๎ดŒ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎žฟ๎œฉ๎žช๎žท๎›พ๎˜‚ ๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚ ๎Ÿข๎˜‚ ๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎˜‚ ๎œข๎œฉ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ด’๎˜‚ ๎™จ๎›พ๎˜‚ ๎ €๎‚๎žฟ๎žข๎›พ๎˜‚ ๎ฏ๎žฟ๎œฉ๎žช๎žท๎žข๎›พ๎˜‚ ๎œฉ๎ฆ๎˜‚ ๎ป๎žข๎Ž๎‚๎œฉ๎ฑ๎˜‚๎œข๎œฉ๎˜‚ ๎ฆ๎ป๎žช๎˜‚
๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎‰๎›พ๎ฑ๎˜‚๎œ›๎›พ๎žฟ๎žช๎›พ๎œข๎ป๎˜‚๎œฉ๎ฑ๎๎œฉ๎žข๎ฏ๎œฉ๎œข๎›พ๎œข๎œฉ๎žช๎˜‚๎Ÿฌ๎ป๎ป๎ฑ๎ผ๎žท๎Ž๎œ›๎›พ๎žช๎ด’๎˜‚๎™จ๎žฟ๎œฉ๎‚๎ป๎˜‚๎ฑ๎ป๎žช๎˜‚๎ฏ๎žฟ๎œฉ๎žช๎žท๎žข๎›พ๎˜‚๎ฆ๎›พ๎˜‚๎ฆ๎ป๎œ›๎›พ๎ฆ๎Ž๎Ÿฌ๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎Ž๎ฑ๎๎œฉ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎žŸ๎›พ๎žข๎›พ๎˜‚๎žŸ๎žข๎ป๎œข๎žฟ๎œ›๎Ž๎žข๎˜‚
๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚๎Ÿข๎˜‚๎ฑ๎ป๎žช๎˜‚๎œข๎œฉ๎žช๎œ›๎žข๎Ž๎œš๎œฉ๎˜‚๎ฆ๎ป๎žช๎˜‚๎žช๎๎ฑ๎žท๎ป๎ฏ๎›พ๎žช๎˜‚๎œ›๎ป๎ฏ๎žฟ๎ฑ๎œฉ๎žช๎˜‚๎Ÿข๎˜‚๎žช๎๎ฑ๎žท๎ป๎ฏ๎›พ๎žช๎˜‚๎œ›๎ฆ๎๎ฑ๎Ž๎œ›๎ป๎žช๎ด’๎˜‚๎˜ƒ๎œข๎Ž๎œ›๎Ž๎ป๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎ฆ๎›พ๎˜‚๎Ž๎ฏ๎›พ๎‚๎œฉ๎ฑ๎˜‚๎ฑ๎ป๎žช๎˜‚๎œข๎›พ๎˜‚๎žฟ๎ฑ๎˜‚๎žŸ๎›พ๎ฑ๎ป๎žข๎›พ๎ฏ๎›พ๎˜‚๎žข๎›ฟ๎žŸ๎Ž๎œข๎ป๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎˜‚
๎žข๎œฉ๎žช๎žŸ๎žฟ๎œฉ๎žช๎žท๎›พ๎˜‚๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚๎œ›๎œฉ๎ฆ๎žฟ๎ฆ๎›พ๎žข๎˜‚๎Ÿข๎˜‚๎‰๎žฟ๎ฏ๎ป๎žข๎›พ๎ฆ๎˜‚๎๎žข๎œฉ๎ฑ๎žท๎œฉ๎˜‚๎›พ๎ฆ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎œ›๎ป๎ฏ๎Ž๎œฉ๎ฑ๎Ÿฌ๎›พ๎˜‚๎œ›๎ป๎ฑ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎™ด๎™ฆ๎˜‚๎Ÿข๎˜‚๎žŸ๎ป๎žช๎žท๎œฉ๎žข๎Ž๎ป๎žข๎˜‚๎›พ๎œ›๎žท๎Ž๎Ÿ›๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎ป๎žช๎˜‚๎ฏ๎›พ๎œ›๎žข๎ผ๎๎›พ๎‚๎ป๎žช๎ด’๎˜‚
๎™จ๎žฟ๎œฉ๎‚๎ป๎ดŒ๎˜‚๎ฆ๎›พ๎˜‚๎›พ๎œ›๎žท๎Ž๎Ÿ›๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎šผ๎˜‚๎๎›พ๎Ÿ›๎ป๎žข๎œฉ๎œ›๎œฉ๎˜‚๎žช๎œฉ๎œ›๎žข๎œฉ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎Ž๎ฑ๎žท๎œฉ๎žข๎๎œฉ๎žข๎ผ๎ฑ๎˜‚๎ดฃ๎™“๎™†๎™ด๎ดค๎˜‚๎Ÿข๎˜‚๎ป๎žท๎žข๎›พ๎žช๎˜‚๎œ›๎Ž๎žท๎ป๎žก๎žฟ๎Ž๎ฑ๎›พ๎žช๎˜‚๎žก๎žฟ๎œฉ๎˜‚๎žข๎œฉ๎๎žฟ๎œฉ๎žข๎Ÿฌ๎›พ๎ฑ๎˜‚๎ฆ๎›พ๎˜‚๎›พ๎œ›๎žท๎Ž๎Ÿ›๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚
๎™ด๎™ฆ๎˜‚๎Ÿข๎˜‚๎ฆ๎ป๎žช๎˜‚๎ฏ๎›พ๎œ›๎žข๎ผ๎๎›พ๎‚๎ป๎žช๎˜‚๎Ÿข๎˜‚๎›พ๎˜‚๎žช๎žฟ๎˜‚๎Ÿ›๎œฉ๎Ÿฌ๎˜‚๎๎›พ๎œ›๎Ž๎ฆ๎Ž๎žท๎›พ๎ฑ๎˜‚๎œข๎Ž๎๎œฉ๎žข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎šผ๎˜‚๎œฉ๎ฑ๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎œฉ๎๎œฉ๎œ›๎žท๎ป๎žข๎›พ๎žช๎˜‚๎šผ๎˜ ๎˜ง๎ฒ—๎ตฏ๎˜‚๎Ÿข๎˜‚๎šผ๎˜ ๎˜ง๎ฒ“๎ตฏ๎ดŒ๎˜‚๎œฉ๎žช๎žท๎›พ๎žช๎˜‚๎Ÿ€๎ฆ๎žท๎Ž๎ฏ๎›พ๎žช๎˜‚๎›พ๎˜‚๎žท๎žข๎›พ๎Ÿ›๎œช๎žช๎˜‚๎œข๎œฉ๎˜‚
๎œ›๎Ž๎žท๎ป๎žก๎žฟ๎Ž๎ฑ๎›พ๎žช๎˜‚๎๎›พ๎Ÿ›๎ป๎žข๎œฉ๎œ›๎œฉ๎ฑ๎˜‚๎ฆ๎›พ๎˜‚๎œข๎Ž๎๎œฉ๎žข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎˜Ÿ๎˜‚๎œฉ๎ฑ๎˜‚๎œ›๎œช๎ฆ๎žฟ๎ฆ๎›พ๎žช๎˜‚๎žŸ๎ฆ๎›พ๎žช๎ฏ๎›ฟ๎žท๎Ž๎œ›๎›พ๎žช๎˜‚๎žŸ๎›พ๎žข๎›พ๎˜‚๎ฆ๎›พ๎˜‚๎œ›๎ป๎ฑ๎žช๎Ž๎‚๎žฟ๎Ž๎œฉ๎ฑ๎žท๎œฉ๎˜‚๎žŸ๎žข๎ป๎œข๎žฟ๎œ›๎œ›๎Ž๎ผ๎ฑ๎˜‚๎œข๎œฉ๎˜‚๎Ž๎ฑ๎ฏ๎žฟ๎ฑ๎ป๎‚๎ฆ๎ป๎œš๎žฟ๎ฆ๎Ž๎ฑ๎›พ๎žช๎˜‚
๎ดฃ๎™“๎‚๎™ฒ๎˜‚๎œฉ๎˜‚๎™“๎‚๎™‡๎ดค๎ด’๎˜‚๎™†๎Ž๎ฑ๎›พ๎ฆ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚๎ฆ๎›พ๎˜‚๎Ž๎ฏ๎›พ๎‚๎œฉ๎ฑ๎˜‚๎ฑ๎ป๎žช๎˜‚๎ฏ๎žฟ๎œฉ๎žช๎žท๎žข๎›พ๎˜‚๎ฆ๎›พ๎˜‚๎žŸ๎ป๎žช๎Ž๎œš๎Ž๎ฆ๎Ž๎œข๎›พ๎œข๎˜‚๎œข๎œฉ๎˜‚๎žท๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎Ž๎ผ๎ฑ๎˜‚๎‰๎žฟ๎ฏ๎›พ๎ฑ๎ป๎˜‚๎›พ๎˜‚๎‰๎žฟ๎ฏ๎›พ๎ฑ๎ป๎ด’
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 | e- issn 2311-2212๎ฒ‘๎ฒ
Tabla 1
Vacunas contra coronavirus que actualmente estรกn es fases clรญnicas
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 |e- issn 2311-2212 ๎ฒ‘๎ฒ
๎˜ ๎ป๎ฑ๎œ›๎ฆ๎žฟ๎žช๎Ž๎ป๎ฑ๎œฉ๎žช
๎šฎ๎Ž๎˜‚ ๎œš๎Ž๎œฉ๎ฑ๎˜‚ ๎ฆ๎ป๎žช๎˜‚ ๎žŸ๎žข๎Ž๎ฏ๎œฉ๎žข๎ป๎žช๎˜‚ ๎œฉ๎žช๎๎žฟ๎œฉ๎žข๎Ÿฌ๎ป๎žช๎˜‚ ๎œ›๎Ž๎œฉ๎ฑ๎žท๎๎ €๎œ›๎ป๎žช๎˜‚ ๎๎žฟ๎œฉ๎žข๎ป๎ฑ๎˜‚
๎ฏ๎žฟ๎Ÿข๎˜‚ ๎ฑ๎ป๎žท๎ป๎žข๎Ž๎ป๎žช๎˜‚ ๎žท๎›พ๎ฆ๎œฉ๎žช๎˜‚ ๎œ›๎ป๎ฏ๎ป๎˜‚ ๎žข๎œฉ๎žŸ๎ป๎žข๎žท๎›พ๎žข๎ดŒ๎˜‚ ๎Ÿ›๎œฉ๎ฆ๎ป๎Ÿฌ๎ฏ๎œฉ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎œฉ๎ฆ๎˜‚
๎‚๎œฉ๎ฑ๎ป๎ฏ๎›พ๎˜‚๎œข๎œฉ๎ฆ๎˜‚๎ฑ๎žฟ๎œฉ๎Ÿ›๎ป๎˜‚๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎ดฃ๎›พ๎‰๎ป๎žข๎›พ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ฒ‘๎ดค๎ดŒ๎˜‚๎Ÿข๎˜‚๎ฆ๎›พ๎˜‚
rรกpida determinaciรณn de los sรญntomas de la enfermedad
๎ดฃ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ดค๎˜‚ ๎žŸ๎›พ๎žข๎›พ๎˜‚ ๎žฟ๎ฑ๎˜‚ ๎ฏ๎œฉ๎ ๎ป๎žข๎˜‚ ๎ฏ๎›พ๎ฑ๎œฉ๎ ๎ป๎˜‚ ๎œ›๎ฆ๎๎ฑ๎Ž๎œ›๎ป๎ดŒ๎˜‚ ๎ฑ๎ป๎˜‚ ๎žช๎œฉ๎˜‚ ๎‰๎›พ๎ฑ๎˜‚
dilucidado completamente los mecanismos celulares y
moleculares del proceso de infecciรณn en humanos.
๎™จ๎ป๎žช๎˜‚๎ฏ๎œช๎žท๎ป๎œข๎ป๎žช๎˜‚๎œข๎œฉ๎˜‚๎œข๎Ž๎›พ๎‚๎ฑ๎ผ๎žช๎žท๎Ž๎œ›๎ป๎˜‚๎ฏ๎ป๎ฆ๎œฉ๎œ›๎žฟ๎ฆ๎›พ๎žข๎œฉ๎žช๎˜‚๎ดฃ๎žŸ๎›พ๎žข๎›พ๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ
๎˜ ๎ป๎›Ÿ๎ฒ‘๎ดค๎˜‚๎Ÿข๎˜‚๎œข๎Ž๎›พ๎‚๎ฑ๎ผ๎žช๎žท๎Ž๎œ›๎ป๎˜‚๎žช๎œฉ๎žข๎ป๎ฆ๎ผ๎‚๎Ž๎œ›๎ป๎˜‚๎ดฃ๎žŸ๎›พ๎žข๎›พ๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎ดค๎˜‚๎‰๎›พ๎ฑ๎˜‚๎žช๎Ž๎œข๎ป๎˜‚
de gran ayuda para el cribado inicial de los infectados,
๎Ÿข๎˜‚๎œ›๎ป๎ฑ๎˜‚๎œฉ๎ฆ๎ฆ๎ป๎ดŒ๎˜‚๎ฏ๎›พ๎Ÿก๎Ž๎ฏ๎Ž๎Ÿฌ๎›พ๎žข๎˜‚๎ฆ๎ป๎žช๎˜‚๎œฉ๎žช๎๎žฟ๎œฉ๎žข๎Ÿฌ๎ป๎žช๎˜‚๎œข๎œฉ๎˜‚๎žท๎ป๎œข๎ป๎žช๎˜‚๎ฆ๎ป๎žช๎˜‚๎žŸ๎›พ๎๎žช๎œฉ๎žช๎˜‚
para facilitar el aislamiento social (cuarentena), aรบn
hay muchas falencias en cuanto a estos mรฉtodos de
diagnรณstico, lo que deja cuestionamientos ligados con
las respuestas inmunitarias humanas.
๎›ƒ๎ฑ๎˜‚ ๎žช๎œฉ๎œ›๎žท๎ป๎žข๎˜‚ ๎œ›๎ป๎ฑ๎žช๎Ž๎œข๎œฉ๎žข๎›พ๎œš๎ฆ๎œฉ๎˜‚ ๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎œ›๎ป๎ฏ๎žฟ๎ฑ๎Ž๎œข๎›พ๎œข๎˜‚ ๎œ›๎Ž๎œฉ๎ฑ๎žท๎๎ €๎œ›๎›พ๎˜‚
habla mucho de los tratamientos para la pandemia,
sin tener evidencia experimental para recomendarlos
puesto que aรบn estรกn en etapa de investigaciรณn
clรญnica; sin embargo, estos tratamientos estรกn siendo
๎žฟ๎žท๎Ž๎ฆ๎Ž๎Ÿฌ๎›พ๎œข๎ป๎žช๎˜‚๎žŸ๎ป๎žข๎˜‚๎ฏ๎žฟ๎œ›๎‰๎ป๎žช๎˜‚๎žŸ๎›พ๎๎žช๎œฉ๎žช๎˜‚๎ดฃ๎Ž๎ฑ๎œ›๎ฆ๎žฟ๎Ÿข๎œฉ๎ฑ๎œข๎ป๎˜‚๎œฉ๎ฆ๎˜‚๎šฃ๎œฉ๎žข๎Ÿ€๎ดค๎˜‚๎œ›๎ป๎ฏ๎ป๎˜‚
terapias alternativas, dejando en la incertidumbre los
efectos colaterales que probablemente se visualicen
ulteriormente a la etapa de crisis sanitaria mundial.
๎šฃ๎ป๎žข๎˜‚๎Ÿ€๎ฆ๎žท๎Ž๎ฏ๎ป๎ดŒ๎˜‚๎žท๎›พ๎ฏ๎œš๎Ž๎œช๎ฑ๎˜‚๎žช๎œฉ๎˜‚๎‰๎›พ๎œš๎ฆ๎›พ๎˜‚๎ฏ๎žฟ๎œ›๎‰๎ป๎˜‚๎žช๎ป๎œš๎žข๎œฉ๎˜‚๎ฆ๎›พ๎žช๎˜‚๎Ÿ›๎›พ๎œ›๎žฟ๎ฑ๎›พ๎žช๎˜‚
y para cuรกndo estarรญan disponibles; sin embargo, lo
๎œ›๎Ž๎œฉ๎žข๎žท๎ป๎˜‚๎œฉ๎žช๎˜‚๎žก๎žฟ๎œฉ๎ดŒ๎˜‚๎›พ๎˜‚๎žŸ๎œฉ๎žช๎›พ๎žข๎˜‚๎œข๎œฉ๎˜‚๎ฆ๎ป๎žช๎˜‚๎‚๎žข๎›พ๎ฑ๎œข๎œฉ๎žช๎˜‚๎œฉ๎žช๎๎žฟ๎œฉ๎žข๎Ÿฌ๎ป๎žช๎˜‚๎œ›๎Ž๎œฉ๎ฑ๎žท๎๎ €๎œ›๎ป๎žช๎ดŒ๎˜‚
ahora solo se dispone de candidatos vacunales que estรกn
en fase de investigaciรณn, desconociรฉndose si tendrรกn
o no la viabilidad requerida para su aplicaciรณn en la
poblaciรณn humana.
๎šฆ๎œฉ๎๎œฉ๎žข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎žช๎˜‚
๎˜ƒ๎‰๎ฏ๎œฉ๎œข๎ดŒ๎˜‚ ๎šฎ๎ด’๎˜‚ ๎™†๎ด’๎ดŒ๎˜‚ ๎šฅ๎žฟ๎›พ๎œข๎œฉ๎œฉ๎žข๎ดŒ๎˜‚ ๎˜ƒ๎ด’๎˜‚ ๎˜ƒ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎™ฒ๎œ›๎™ฆ๎›พ๎Ÿข๎ดŒ๎˜‚๎™ฒ๎ด’๎˜‚ ๎šฆ๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚
๎šฃ๎žข๎œฉ๎ฆ๎Ž๎ฏ๎Ž๎ฑ๎›พ๎žข๎Ÿข๎˜‚ ๎™“๎œข๎œฉ๎ฑ๎žท๎Ž๎ €๎œ›๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚ ๎ป๎๎˜‚ ๎šฃ๎ป๎žท๎œฉ๎ฑ๎žท๎Ž๎›พ๎ฆ๎˜‚ ๎›Ÿ๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚
๎šผ๎›พ๎žข๎‚๎œฉ๎žท๎žช๎˜‚ ๎๎ป๎žข๎˜‚ ๎žท๎‰๎œฉ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎˜ ๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎ดฃ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ
๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎ดค๎˜‚ ๎˜Ÿ๎›พ๎žช๎œฉ๎œข๎˜‚ ๎ป๎ฑ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎˜‚ Immunological
Studies. Viruses, 12(3), 254. https://doi.org/10.3390/
v12030254
๎˜ƒ๎ฆ๎ป๎žช๎›พ๎Ž๎ฏ๎Ž๎ดŒ๎˜‚๎˜Ÿ๎ด’๎ดŒ๎˜‚๎™Ž๎›พ๎ฏ๎œฉ๎œข๎ดŒ๎˜‚๎™ฒ๎ด’๎˜‚๎˜ฏ๎ด’๎ดŒ๎˜‚๎™ด๎›พ๎œฉ๎œฉ๎ฏ๎ดŒ๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚๎˜ƒ๎ฆ๎žช๎‰๎›พ๎žข๎œฉ๎๎ดŒ๎˜‚๎˜ƒ๎ด’๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚
๎˜ƒ๎ฆ๎šฅ๎›พ๎‰๎žท๎›พ๎ฑ๎Ž๎ดŒ๎˜‚๎šฎ๎ด’๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎˜ƒ๎ฆ๎˜ง๎ป๎žช๎›พ๎žข๎Ž๎ดŒ๎˜‚๎™ฆ๎ด’๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎˜ƒ๎ฆ๎›พ๎ฏ๎žข๎Ž๎ดŒ๎˜‚๎˜ƒ๎ด’๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚
๎˜ƒ๎ฆ๎ดฎ๎˜ฏ๎Ž๎žช๎›พ๎ดŒ๎˜‚ ๎™ฆ๎ด’๎ดŒ๎˜‚ ๎™ฆ๎‰๎ป๎ ๎›พ๎‰๎ดŒ๎˜‚ ๎šผ๎ด’๎ดŒ๎˜‚ ๎˜ƒ๎žช๎žช๎Ž๎žข๎Ž๎ดŒ๎˜‚ ๎˜ƒ๎ด’๎˜‚ ๎™ฒ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎˜ฏ๎ฑ๎›พ๎ฑ๎Ž๎ดŒ๎˜‚
๎™ฒ๎ด’๎˜‚๎˜ƒ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎™ฒ๎˜ฏ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎˜‚๎Ž๎ฑ๎๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎˜‚๎Ž๎žช๎˜‚๎›พ๎žช๎žช๎ป๎œ›๎Ž๎›พ๎žท๎œฉ๎œข๎˜‚
๎Ÿœ๎Ž๎žท๎‰๎˜‚ ๎œข๎ป๎Ÿœ๎ฑ๎žข๎œฉ๎‚๎žฟ๎ฆ๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚ ๎ป๎๎˜‚ ๎‚๎œฉ๎ฑ๎œฉ๎žช๎˜‚ ๎œฉ๎ฑ๎œ›๎ป๎œข๎Ž๎ฑ๎‚๎˜‚ ๎ ƒ๎ฒ๎˜‚
๎›พ๎ฑ๎œข๎˜‚ ๎ ƒ๎ฒ‘๎˜‚ ๎œ›๎Ÿข๎žท๎ป๎ฃ๎Ž๎ฑ๎œฉ๎žช๎ด˜๎œ›๎‰๎œฉ๎ฏ๎ป๎ฃ๎Ž๎ฑ๎œฉ๎žช๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎œฉ๎ฆ๎œฉ๎Ÿ›๎›พ๎žท๎œฉ๎œข๎˜‚
๎Ž๎ฑ๎Ÿด๎ฆ๎›พ๎ฏ๎ฏ๎›พ๎žท๎ป๎žข๎Ÿข๎˜‚ ๎Ž๎ฑ๎ฑ๎›พ๎žท๎œฉ๎˜‚ ๎Ž๎ฏ๎ฏ๎žฟ๎ฑ๎œฉ๎˜‚ ๎žข๎œฉ๎žช๎žŸ๎ป๎ฑ๎žช๎œฉ๎˜‚ ๎Ž๎ฑ๎˜‚ ๎žท๎‰๎œฉ๎˜‚
๎ฆ๎ป๎Ÿœ๎œฉ๎žข๎˜‚๎žข๎œฉ๎žช๎žŸ๎Ž๎žข๎›พ๎žท๎ป๎žข๎Ÿข๎˜‚๎žท๎žข๎›พ๎œ›๎žท๎ด’๎˜‚Cytokine, 126, 154895.
๎˜ ๎›พ๎žข๎Ÿ›๎›พ๎ฆ๎‰๎ป๎ดŒ๎˜‚๎šผ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚๎šฆ๎œฉ๎žช๎œฉ๎›พ๎žข๎œ›๎‰๎˜‚๎Ž๎ฑ๎˜‚๎˜Ÿ๎žข๎Ž๎œฉ๎๎ด‹๎˜‚๎ฒ“๎˜‚๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚
๎žท๎ป๎˜‚ ๎ฒ๎ฒ๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด’๎˜‚ Nature Medicine. https://doi.
org/10.1038/d41591-020-00009-x
๎˜ ๎‰๎›พ๎ฑ๎ดŒ๎˜‚๎™ค๎ด’๎˜‚๎™†๎ด’๎ดฎ๎› ๎ด’๎ดŒ๎˜‚๎›ฆ๎žฟ๎›พ๎ฑ๎ดŒ๎˜‚๎šฎ๎ด’๎ดŒ๎˜‚๎™ฆ๎ป๎ฃ๎ดŒ๎˜‚๎™ฆ๎ด’๎ดฎ๎™Ž๎ด’๎ดŒ๎˜‚๎šผ๎ป๎ดŒ๎˜‚๎™ฆ๎ด’๎˜‚๎™ฆ๎ด’๎ดฎ๎› ๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎žฟ๎ดŒ๎˜‚
๎™Ž๎ด’๎ดŒ๎˜‚๎›ฆ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎›ฅ๎Ž๎ฑ๎‚๎ดŒ๎˜‚๎™†๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎›ฆ๎Ž๎žŸ๎ดŒ๎˜‚๎˜ ๎ด’๎˜‚๎˜ ๎ด’๎ดฎ๎›ฆ๎ด’๎ดŒ๎˜‚๎šฃ๎ป๎ป๎ฑ๎ดŒ๎˜‚
๎šฆ๎ด’๎˜‚๎› ๎ด’๎ดฎ๎šฎ๎ด’๎ดŒ๎˜‚๎šผ๎žช๎ป๎Ž๎ดŒ๎˜‚๎™Ž๎ด’๎ดฎ๎› ๎ด’๎ดŒ๎˜‚๎™จ๎ป๎ดŒ๎˜‚๎šฎ๎ด’๎˜‚๎™ฆ๎ด’๎ดฎ๎™†๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎›พ๎ฑ๎ดŒ๎˜‚๎™ฆ๎ด’๎ดฎ๎™Ž๎ด’๎ดŒ๎˜‚
๎šฃ๎ป๎ป๎ฑ๎ดŒ๎˜‚๎›Ÿ๎ด’๎˜‚๎™ฆ๎ด’๎ดฎ๎™ฒ๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎›พ๎ฑ๎ดŒ๎˜‚๎› ๎ด’๎ดฎ๎™ฒ๎ด’๎ดŒ๎˜‚๎™“๎žŸ๎ดŒ๎˜‚๎™ค๎ด’๎˜‚๎˜ง๎ด’๎ดŒ๎˜‚๎˜ ๎›พ๎Ž๎ดŒ๎˜‚๎™ค๎ด’๎ดฎ๎šฃ๎ด’๎ดŒ๎˜‚
Cheng, V. C.-C., Chen, H., โ€ฆ Yuen, K.-Y. (2020).
๎˜ƒ๎˜‚๎๎›พ๎ฏ๎Ž๎ฆ๎Ž๎›พ๎ฆ๎˜‚๎œ›๎ฆ๎žฟ๎žช๎žท๎œฉ๎žข๎˜‚๎ป๎๎˜‚๎žŸ๎ฑ๎œฉ๎žฟ๎ฏ๎ป๎ฑ๎Ž๎›พ๎˜‚๎›พ๎žช๎žช๎ป๎œ›๎Ž๎›พ๎žท๎œฉ๎œข๎˜‚๎Ÿœ๎Ž๎žท๎‰๎˜‚
the 2019 novel coronavirus indicating person-to-
person transmission: a study of a family cluster.
๎ „๎œฉ๎˜‚๎™จ๎›พ๎ฑ๎œ›๎œฉ๎žท, 395(10223), 514โ€“523.
๎˜ ๎‰๎›พ๎ฑ๎ฑ๎›พ๎žŸ๎žŸ๎›พ๎ฑ๎›พ๎Ÿ›๎›พ๎žข๎ดŒ๎˜‚๎šฆ๎ด’๎ดŒ๎˜‚๎™†๎œฉ๎‰๎žข๎ดŒ๎˜‚๎˜ƒ๎ด’๎˜‚๎šฆ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎œฉ๎ฑ๎‚๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎› ๎ป๎‰๎ฆ๎๎ป๎žข๎œข๎ดฎ
๎™จ๎œฉ๎ฑ๎›พ๎ฑ๎œฉ๎ดŒ๎˜‚ ๎˜ ๎ด’๎ดŒ๎˜‚ ๎˜ƒ๎œš๎žข๎›พ๎‰๎›พ๎ฑ๎žท๎œฉ๎ดŒ๎˜‚ ๎™ค๎ด’๎˜‚ ๎˜ฏ๎ด’๎ดŒ๎˜‚ ๎™ฒ๎›พ๎œ›๎ฃ๎ดŒ๎˜‚ ๎™ฒ๎ด’๎ดŒ๎˜‚
๎šฎ๎ป๎ฏ๎žŸ๎›พ๎ฆ๎ฆ๎›พ๎œฉ๎ดŒ๎˜‚ ๎šฆ๎ด’๎ดŒ๎˜‚ ๎™ฒ๎œ›๎˜ ๎žข๎›พ๎Ÿข๎ดŒ๎˜‚ ๎šฃ๎ด’๎˜‚ ๎˜Ÿ๎ด’๎ดŒ๎˜‚ ๎™ค๎žข๎ดŒ๎˜‚ ๎™ฒ๎œฉ๎Ÿข๎œฉ๎žข๎‰๎ป๎ฆ๎Ÿฌ๎ดŒ๎˜‚ ๎˜ง๎ด’๎˜‚
๎™ฆ๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎šฃ๎œฉ๎žข๎ฆ๎ฏ๎›พ๎ฑ๎ดŒ๎˜‚๎šฎ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚๎™“๎™†๎™ด๎ดฎ๎™“๎˜‚๎žข๎œฉ๎žช๎žŸ๎ป๎ฑ๎žช๎œฉ๎˜‚๎žท๎Ž๎ฏ๎Ž๎ฑ๎‚๎˜‚
๎žข๎œฉ๎ฆ๎›พ๎žท๎Ž๎Ÿ›๎œฉ๎˜‚ ๎žท๎ป๎˜‚ ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎žข๎œฉ๎žŸ๎ฆ๎Ž๎œ›๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚ ๎œข๎œฉ๎žท๎œฉ๎žข๎ฏ๎Ž๎ฑ๎œฉ๎žช๎˜‚ ๎™ฒ๎˜ฏ๎šฆ๎šฎ๎˜‚
coronavirus infection outcomes. ๎ „๎œฉ๎˜‚ ๎™ค๎ป๎žฟ๎žข๎ฑ๎›พ๎ฆ๎˜‚ ๎ป๎๎˜‚
Clinical Investigation, 130, 3625โ€“3639.
๎˜ ๎‰๎œฉ๎ฑ๎ดŒ๎˜‚๎› ๎ด’๎˜‚๎™Ž๎ด’๎ดŒ๎˜‚๎šฎ๎žท๎žข๎Ÿข๎œ›๎‰๎ดŒ๎˜‚๎›ƒ๎ด’๎ดŒ๎˜‚๎™Ž๎ป๎žท๎œฉ๎Ÿฌ๎ดŒ๎˜‚๎šฃ๎ด’๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎˜Ÿ๎ป๎žท๎žท๎›พ๎Ÿฌ๎Ÿฌ๎Ž๎ดŒ๎˜‚๎™ฒ๎ด’๎˜‚๎˜ฏ๎ด’๎˜‚
๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ ๎ ƒ๎œฉ๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚ ๎›Ÿ๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚ ๎šฃ๎Ž๎žŸ๎œฉ๎ฆ๎Ž๎ฑ๎œฉ๎ด‹๎˜‚ ๎›พ๎ฑ๎˜‚
๎™ฟ๎Ÿ›๎œฉ๎žข๎Ÿ›๎Ž๎œฉ๎Ÿœ๎ด’๎˜‚ Current Tropical Medicine Reports, pp.
1โ€“4. https://doi.org/10.1007/s40475-020-00201-6
๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎šผ๎žข๎Ž๎›พ๎ฆ๎žช๎ด’๎‚๎ป๎Ÿ›๎ด’๎˜‚ ๎ดฃ๎ฑ๎ด’๎œข๎ด’๎ดค๎ด’๎˜‚ ๎šฃortal institutional. Retrieved
๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚๎ฒ๎ฒ‘๎ดŒ๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚๎๎žข๎ป๎ฏ๎˜‚๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎œ›๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎žท๎žข๎Ž๎›พ๎ฆ๎žช๎ด’๎‚๎ป๎Ÿ›๎ด˜
๎˜ ๎ป๎žข๎ฏ๎›พ๎ฑ๎ดŒ๎˜‚๎›Ÿ๎ด’๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎™จ๎›พ๎ฑ๎œข๎žท๎ดŒ๎˜‚๎™ฟ๎ด’๎ดŒ๎˜‚๎™ฆ๎›พ๎Ž๎žช๎œฉ๎žข๎ดŒ๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎™ฒ๎ป๎ฆ๎œฉ๎ฑ๎ฃ๎›พ๎ฏ๎žŸ๎ดŒ๎˜‚๎šฆ๎ด’๎ดŒ๎˜‚
๎™ฒ๎œฉ๎Ž๎ ๎œฉ๎žข๎ดŒ๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎žฟ๎ดŒ๎˜‚๎˜ง๎ด’๎˜‚๎™ฆ๎ด’๎˜‚๎› ๎ด’๎ดŒ๎˜‚๎˜Ÿ๎ฆ๎œฉ๎Ž๎œ›๎ฃ๎œฉ๎žข๎ดŒ๎˜‚๎šผ๎ด’๎ดŒ๎˜‚๎˜Ÿ๎žข๎Ÿ…๎ฑ๎Ž๎ฑ๎ฃ๎ดŒ๎˜‚
๎šฎ๎ด’๎ดŒ๎˜‚๎šฎ๎œ›๎‰๎ฑ๎œฉ๎Ž๎œข๎œฉ๎žข๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎šฎ๎œ›๎‰๎ฏ๎Ž๎œข๎žท๎ดŒ๎˜‚๎™ฒ๎ด’๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎™ฒ๎žฟ๎ฆ๎œข๎œฉ๎žข๎žช๎ดŒ๎˜‚๎˜ง๎ด’๎˜‚๎™‡๎ด’๎˜‚
๎™ค๎ด’๎˜‚๎˜ ๎ด’๎ดŒ๎˜‚๎™Ž๎›พ๎›พ๎‚๎ฏ๎›พ๎ฑ๎žช๎ดŒ๎˜‚๎˜Ÿ๎ด’๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎Ÿ›๎›พ๎ฑ๎˜‚๎œข๎œฉ๎žข๎˜‚๎›Ÿ๎œฉ๎œฉ๎žข๎ดŒ๎˜‚๎˜Ÿ๎ด’๎ดŒ๎˜‚๎Ÿ›๎›พ๎ฑ๎˜‚๎œข๎œฉ๎ฑ๎˜‚
๎˜Ÿ๎žข๎Ž๎ฑ๎ฃ๎ดŒ๎˜‚ ๎šฎ๎ด’๎ดŒ๎˜‚ ๎› ๎Ž๎ ๎žช๎ฏ๎›พ๎ฑ๎ดŒ๎˜‚ ๎™จ๎ด’๎ดŒ๎˜‚ ๎™‡๎ป๎œข๎œฉ๎žข๎žช๎ฃ๎Ž๎ดŒ๎˜‚ ๎™‡๎ด’๎ดŒ๎˜‚ ๎šฆ๎ป๎ฏ๎œฉ๎žท๎žท๎œฉ๎ดŒ๎˜‚
๎™ค๎ด’๎ดฎ๎™จ๎ด’๎ดŒ๎˜‚๎˜ฏ๎ฆ๎ฆ๎Ž๎žช๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎›ฐ๎›พ๎ฏ๎œš๎ป๎ฑ๎ดŒ๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎ด๎˜‚๎˜ง๎žข๎ป๎žช๎žท๎œฉ๎ฑ๎ดŒ๎˜‚๎˜ ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚
๎˜ง๎œฉ๎žท๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎˜‚๎ป๎๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎˜‚๎ฑ๎ป๎Ÿ›๎œฉ๎ฆ๎˜‚๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดฎ๎ฑ๎˜ ๎ป๎›Ÿ๎ดค๎˜‚
๎œš๎Ÿข๎˜‚๎žข๎œฉ๎›พ๎ฆ๎ดฎ๎žท๎Ž๎ฏ๎œฉ๎˜‚๎šฆ๎šผ๎ดฎ๎šฃ๎˜ ๎šฆ๎ด’๎˜‚๎˜ฏ๎žฟ๎žข๎ป๎˜‚๎šฎ๎žฟ๎žข๎Ÿ›๎œฉ๎Ž๎ฆ๎ฆ๎›พ๎ฑ๎œ›๎œฉ๎ด‹๎˜‚Bulletin
๎˜ฏ๎žฟ๎žข๎ป๎žŸ๎œฉ๎œฉ๎ฑ๎˜‚๎šฎ๎žฟ๎žข๎˜‚๎™จ๎œฉ๎žช๎˜‚๎™ฒ๎›พ๎ฆ๎›พ๎œข๎Ž๎œฉ๎žช๎˜‚๎šผ๎žข๎›พ๎ฑ๎žช๎ฏ๎Ž๎žช๎žช๎Ž๎œš๎ฆ๎œฉ๎žช๎˜‚๎ตน๎˜‚๎˜ฏ๎žฟ๎žข๎ป๎žŸ๎œฉ๎›พ๎ฑ๎˜‚
Communicable Disease Bulletin, 25(3). https://doi.
๎ป๎žข๎‚๎ด˜๎ฒ๎ฒ๎ด’๎ฒ‘๎ฒ—๎ฒ๎ฒ–๎ด˜๎ฒ๎ฒ”๎ฒ•๎ฒ๎ดฎ๎ฒ–๎ฒ˜๎ฒ๎ฒ–๎ด’๎˜ฏ๎šฎ๎ด’๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด’๎ฒ‘๎ฒ”๎ด’๎ฒ’๎ด’๎ฒ‘๎ฒ๎ฒ๎ฒ๎ฒ๎ฒ“๎ฒ”
๎˜ ๎žฟ๎Ž๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ดŒ๎˜‚๎™†๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎šฎ๎‰๎Ž๎ดŒ๎˜‚๎›ฐ๎ด’๎ดฎ๎™จ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚๎™ฟ๎žข๎Ž๎‚๎Ž๎ฑ๎˜‚๎›พ๎ฑ๎œข๎˜‚๎œฉ๎Ÿ›๎ป๎ฆ๎žฟ๎žท๎Ž๎ป๎ฑ๎˜‚
of pathogenic coronaviruses. Nature Reviews.
Microbiology, 17(3), 181โ€“192.
๎˜ง๎ป๎ฑ๎‚๎ดŒ๎˜‚๎˜ฏ๎ด’๎ดŒ๎˜‚๎˜ง๎žฟ๎ดŒ๎˜‚๎™Ž๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎™‡๎›พ๎žข๎œข๎ฑ๎œฉ๎žข๎ดŒ๎˜‚๎™จ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ƒ๎ฑ๎˜‚๎Ž๎ฑ๎žท๎œฉ๎žข๎›พ๎œ›๎žท๎Ž๎Ÿ›๎œฉ๎˜‚
๎Ÿœ๎œฉ๎œš๎ดฎ๎œš๎›พ๎žช๎œฉ๎œข๎˜‚๎œข๎›พ๎žช๎‰๎œš๎ป๎›พ๎žข๎œข๎˜‚๎žท๎ป๎˜‚๎žท๎žข๎›พ๎œ›๎ฃ๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚๎Ž๎ฑ๎˜‚๎žข๎œฉ๎›พ๎ฆ๎˜‚
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 | e- issn 2311-2212๎ฒ‘๎ฒ‘
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๎ป๎žข๎‚๎ด˜๎ฒ๎ฒ๎ด’๎ฒ๎ฒ๎ฒ๎ฒ•๎ด˜๎šฎ๎ฒ๎ฒ“๎ฒ–๎ฒ’๎ดฎ๎ฒ’๎ฒ๎ฒ˜๎ฒ˜๎ดฃ๎ฒ‘๎ฒ๎ดค๎ฒ’๎ฒ๎ฒ๎ฒ‘๎ฒ๎ดฎ๎ฒ
๎™†๎›พ๎ฑ๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดŒ๎˜‚ ๎›ฐ๎‰๎›พ๎ป๎ดŒ๎˜‚ ๎™ฆ๎ด’๎ดŒ๎˜‚ ๎šฎ๎‰๎Ž๎ดŒ๎˜‚ ๎›ฐ๎ด’๎ดฎ๎™จ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎›ฐ๎‰๎ป๎žฟ๎ดŒ๎˜‚ ๎šฃ๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚ ๎˜Ÿ๎›พ๎žท๎˜‚
Coronaviruses in China. Viruses, 11(3). https://doi.
org/10.3390/v11030210
๎™‡๎ป๎žข๎œš๎›พ๎ฆ๎œฉ๎ฑ๎Ÿข๎›พ๎ดŒ๎˜‚๎šฎ๎ด’๎˜ ๎ด’๎˜‚๎œฉ๎žท๎˜‚๎›พ๎ฆ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎ ƒ๎œฉ๎˜‚๎žช๎žŸ๎œฉ๎œ›๎Ž๎œฉ๎žช๎˜‚๎šฎ๎œฉ๎Ÿ›๎œฉ๎žข๎œฉ๎˜‚๎›พ๎œ›๎žฟ๎žท๎œฉ๎˜‚
respiratory syndrome-related coronavirus:
๎œ›๎ฆ๎›พ๎žช๎žช๎Ž๎๎Ÿข๎Ž๎ฑ๎‚๎˜‚ ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดฎ๎ฑ๎˜ ๎ป๎›Ÿ๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎ฑ๎›พ๎ฏ๎Ž๎ฑ๎‚๎˜‚ ๎Ž๎žท๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ
CoV-2. Nat. Microbiol. (2020), 10.1038/s41564-
๎ฒ๎ฒ‘๎ฒ๎ดฎ๎ฒ๎ฒ•๎ฒ˜๎ฒ”๎ดฎ๎Ÿฌ
๎™Ž๎ป๎Ÿฒ๎๎ฏ๎›พ๎ฑ๎ฑ๎ดŒ๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎™ฆ๎ฆ๎œฉ๎Ž๎ฑ๎œฉ๎ดฎ๎› ๎œฉ๎œš๎œฉ๎žข๎ดŒ๎˜‚๎™Ž๎ด’๎ดŒ๎˜‚๎šฎ๎œ›๎‰๎žข๎ป๎œฉ๎œข๎œฉ๎žข๎ดŒ๎˜‚๎šฎ๎ด’๎ดŒ๎˜‚๎™ฆ๎žข๎Ÿ…๎‚๎œฉ๎žข๎ดŒ๎˜‚
๎™ด๎ด’๎ดŒ๎˜‚ ๎™Ž๎œฉ๎žข๎žข๎ฆ๎œฉ๎žข๎ดŒ๎˜‚ ๎šผ๎ด’๎ดŒ๎˜‚ ๎˜ฏ๎žข๎Ž๎œ›๎‰๎žช๎œฉ๎ฑ๎ดŒ๎˜‚ ๎šฎ๎ด’๎ดŒ๎˜‚ ๎šฎ๎œ›๎‰๎Ž๎œฉ๎žข๎‚๎œฉ๎ฑ๎žช๎ดŒ๎˜‚ ๎šผ๎ด’๎˜‚ ๎šฎ๎ด’๎ดŒ๎˜‚
๎™Ž๎œฉ๎žข๎žข๎ฆ๎œฉ๎žข๎ดŒ๎˜‚ ๎™‡๎ด’๎ดŒ๎˜‚ ๎› ๎žฟ๎ดŒ๎˜‚ ๎™ด๎ด’๎ดฎ๎™Ž๎ด’๎ดŒ๎˜‚ ๎™ด๎Ž๎žท๎žช๎œ›๎‰๎œฉ๎ดŒ๎˜‚ ๎˜ƒ๎ด’๎ดŒ๎˜‚ ๎™ฒ๎Ÿ…๎ฆ๎ฆ๎œฉ๎žข๎ดŒ๎˜‚
๎™ฒ๎ด’๎˜‚ ๎˜ƒ๎ด’๎ดŒ๎˜‚ ๎˜ง๎žข๎ป๎žช๎žท๎œฉ๎ฑ๎ดŒ๎˜‚ ๎˜ ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎šฃ๎ž†๎‰๎ฆ๎ฏ๎›พ๎ฑ๎ฑ๎ดŒ๎˜‚ ๎šฎ๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚
๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚ ๎˜ ๎œฉ๎ฆ๎ฆ๎˜‚ ๎˜ฏ๎ฑ๎žท๎žข๎Ÿข๎˜‚ ๎˜ง๎œฉ๎žŸ๎œฉ๎ฑ๎œข๎žช๎˜‚ ๎ป๎ฑ๎˜‚ ๎˜ƒ๎˜ ๎˜ฏ๎ฒ‘๎˜‚ ๎›พ๎ฑ๎œข๎˜‚
๎šผ๎™ฒ๎šฃ๎šฆ๎šฎ๎šฎ๎ฒ‘๎˜‚๎›พ๎ฑ๎œข๎˜‚ ๎™“๎žช๎˜‚๎˜Ÿ๎ฆ๎ป๎œ›๎ฃ๎œฉ๎œข๎˜‚๎œš๎Ÿข๎˜‚๎›พ๎˜‚๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎ฆ๎Ÿข๎˜‚๎šฃ๎žข๎ป๎Ÿ›๎œฉ๎ฑ๎˜‚
๎šฃ๎žข๎ป๎žท๎œฉ๎›พ๎žช๎œฉ๎˜‚๎™“๎ฑ๎‰๎Ž๎œš๎Ž๎žท๎ป๎žข๎ด’๎˜‚Cell. https://doi.org/10.1016/j.
cell.2020.02.052
๎™Ž๎žฟ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎˜ ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดŒ๎˜‚ ๎™จ๎Ž๎ดŒ๎˜‚ ๎›ฅ๎ด’๎ดŒ๎˜‚ ๎šฆ๎œฉ๎ฑ๎ดŒ๎˜‚ ๎™จ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎›พ๎ป๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚ ๎™Ž๎žฟ๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดŒ๎˜‚
๎›ฐ๎‰๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎™†๎›พ๎ฑ๎ดŒ๎˜‚๎™‡๎ด’๎ดŒ๎˜‚๎›ฅ๎žฟ๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎™‡๎žฟ๎ดŒ๎˜‚๎›ฅ๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎œฉ๎ฑ๎‚๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎›ฆ๎žฟ๎ดŒ๎˜‚
T., Xia, J., Wei, Y., Wu, W., Xie, X., Yin, W., Li,
๎™Ž๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎ด๎˜‚๎˜ ๎›พ๎ป๎ดŒ๎˜‚๎˜Ÿ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎˜‚๎๎œฉ๎›พ๎žท๎žฟ๎žข๎œฉ๎žช๎˜‚๎ป๎๎˜‚
๎žŸ๎›พ๎žท๎Ž๎œฉ๎ฑ๎žท๎žช๎˜‚๎Ž๎ฑ๎๎œฉ๎œ›๎žท๎œฉ๎œข๎˜‚๎Ÿœ๎Ž๎žท๎‰๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎˜‚๎ฑ๎ป๎Ÿ›๎œฉ๎ฆ๎˜‚๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚๎Ž๎ฑ๎˜‚
Wuhan, China. ๎ „๎œฉ๎˜‚๎™จ๎›พ๎ฑ๎œ›๎œฉ๎žท, 395(10223), 497โ€“506.
๎™จ๎›พ๎ฏ๎ดŒ๎˜‚ ๎šผ๎ด’๎˜‚ ๎šผ๎ด’๎ดฎ๎›ฆ๎ด’๎ดŒ๎˜‚ ๎šฎ๎‰๎žฟ๎ฏ๎ดŒ๎˜‚ ๎™ฒ๎ด’๎˜‚ ๎™Ž๎ด’๎ดฎ๎™Ž๎ด’๎ดŒ๎˜‚ ๎›ฐ๎‰๎žฟ๎ดŒ๎˜‚ ๎™Ž๎ด’๎ดฎ๎˜ ๎ด’๎ดŒ๎˜‚ ๎šผ๎ป๎ฑ๎‚๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดฎ
๎™‡๎ด’๎ดŒ๎˜‚ ๎™ด๎Ž๎ดŒ๎˜‚ ๎›ฅ๎ด’๎ดฎ๎˜Ÿ๎ด’๎ดŒ๎˜‚ ๎™จ๎Ž๎›พ๎ป๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดฎ๎šฎ๎ด’๎ดŒ๎˜‚ ๎› ๎œฉ๎Ž๎ดŒ๎˜‚ ๎› ๎ด’๎ดŒ๎˜‚ ๎˜ ๎‰๎œฉ๎žฟ๎ฑ๎‚๎ดŒ๎˜‚ ๎› ๎ด’๎˜‚
๎›ฆ๎ด’๎ดฎ๎™ฒ๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ดŒ๎˜‚๎› ๎ด’๎ดฎ๎™ค๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ดŒ๎˜‚๎™จ๎ด’๎ดฎ๎™†๎ด’๎ดŒ๎˜‚๎™จ๎œฉ๎žฟ๎ฑ๎‚๎ดŒ๎˜‚๎™‡๎ด’๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎™Ž๎ป๎ฆ๎ฏ๎œฉ๎žช๎ดŒ๎˜‚
๎˜ฏ๎ด’๎˜‚๎˜ ๎ด’๎ดŒ๎˜‚๎™Ž๎žฟ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดฎ๎™จ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎™‡๎žฟ๎›พ๎ฑ๎ดŒ๎˜‚ ๎›ฆ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎™“๎œข๎œฉ๎ฑ๎žท๎Ž๎๎Ÿข๎Ž๎ฑ๎‚๎˜‚
๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚ ๎žข๎œฉ๎ฆ๎›พ๎žท๎œฉ๎œข๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎œฉ๎žช๎˜‚ ๎Ž๎ฑ๎˜‚ Malayan
pangolins. Nature. https://doi.org/10.1038/s41586-
020-2169-0
๎™จ๎Ž๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎›ฆ๎Ž๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎™จ๎žฟ๎ป๎ดŒ๎˜‚๎›ฅ๎ด’๎ดŒ๎˜‚๎›ฅ๎Ž๎ป๎ฑ๎‚๎ดŒ๎˜‚๎™ด๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ดŒ๎˜‚๎šฎ๎ด’๎ดŒ๎˜‚๎šฎ๎žฟ๎ฑ๎ดŒ๎˜‚๎šฆ๎ด’๎ดŒ๎˜‚
๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎™Ž๎žฟ๎ดŒ๎˜‚๎˜Ÿ๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎œฉ๎ฑ๎ดŒ๎˜‚๎› ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚
๎™Ž๎žฟ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎˜Ÿ๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ฑ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎›ฆ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎˜ ๎›พ๎Ž๎ดŒ๎˜‚๎› ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎›ฅ๎ด’๎ดŒ๎˜‚
๎˜ ๎‰๎œฉ๎ฑ๎‚๎ดŒ๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎˜ ๎‰๎œฉ๎ฑ๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎ด๎˜‚๎›ฆ๎œฉ๎ดŒ๎˜‚๎™†๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ง๎œฉ๎Ÿ›๎œฉ๎ฆ๎ป๎žŸ๎ฏ๎œฉ๎ฑ๎žท๎˜‚
๎›พ๎ฑ๎œข๎˜‚ ๎˜ ๎ฆ๎Ž๎ฑ๎Ž๎œ›๎›พ๎ฆ๎˜‚ ๎˜ƒ๎žŸ๎žŸ๎ฆ๎Ž๎œ›๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚ ๎ป๎๎˜‚ ๎˜ƒ๎˜‚ ๎šฆ๎›พ๎žŸ๎Ž๎œข๎˜‚ ๎™“๎‚๎™ฒ๎ดฎ๎™“๎‚๎™‡๎˜‚
๎˜ ๎ป๎ฏ๎œš๎Ž๎ฑ๎œฉ๎œข๎˜‚๎˜ƒ๎ฑ๎žท๎Ž๎œš๎ป๎œข๎Ÿข๎˜‚๎šผ๎œฉ๎žช๎žท๎˜‚๎๎ป๎žข๎˜‚๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚Infection
๎˜ง๎Ž๎›พ๎‚๎ฑ๎ป๎žช๎Ž๎žช๎ด˜๎˜‚๎™ค๎ป๎žฟ๎žข๎ฑ๎›พ๎ฆ๎˜‚๎ป๎๎˜‚๎™ฒ๎œฉ๎œข๎Ž๎œ›๎›พ๎ฆ๎˜‚๎›Ÿ๎Ž๎žข๎ป๎ฆ๎ป๎‚๎Ÿข. https://doi.
org/10.1002/jmv.25727
๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎˜ ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎ป๎žฟ๎ดŒ๎˜‚ ๎šฅ๎ด’๎ดŒ๎˜‚ ๎™จ๎Ž๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดŒ๎˜‚๎™‡๎›พ๎žข๎ฑ๎œฉ๎žข๎ดŒ๎˜‚ ๎™จ๎ด’๎˜‚ ๎›Ÿ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎žท๎ฃ๎Ž๎ฑ๎žช๎ดŒ๎˜‚ ๎šฎ๎ด’๎˜‚ ๎šฃ๎ด’๎ดŒ๎˜‚
๎˜ ๎›พ๎žข๎žท๎œฉ๎žข๎ดŒ๎˜‚๎™จ๎ด’๎˜‚๎™ค๎ด’๎ดŒ๎˜‚๎ด๎˜‚๎˜ƒ๎ฆ๎œš๎›พ๎Ž๎žฟ๎ดŒ๎˜‚๎˜ง๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎›พ๎ดค๎ด’๎˜‚๎šฆ๎œฉ๎žช๎œฉ๎›พ๎žข๎œ›๎‰๎˜‚๎›พ๎ฑ๎œข๎˜‚
๎˜ง๎œฉ๎Ÿ›๎œฉ๎ฆ๎ป๎žŸ๎ฏ๎œฉ๎ฑ๎žท๎˜‚๎ป๎ฑ๎˜‚๎ ƒ๎œฉ๎žข๎›พ๎žŸ๎œฉ๎žฟ๎žท๎Ž๎œ›๎˜‚๎˜ƒ๎‚๎œฉ๎ฑ๎žท๎žช๎˜‚๎›พ๎ฑ๎œข๎˜‚๎›Ÿ๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎žช๎˜‚
๎๎ป๎žข๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎›พ๎ฑ๎œข๎˜‚ ๎šฆ๎œฉ๎ฆ๎›พ๎žท๎œฉ๎œข๎˜‚๎™Ž๎žฟ๎ฏ๎›พ๎ฑ๎˜‚ ๎˜ ๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚
๎˜ง๎Ž๎žช๎œฉ๎›พ๎žช๎œฉ๎žช๎ด’๎˜‚ ACS Central Science, 6(3), 315โ€“331.
https://doi.org/10.1021/acscentsci.0c00272
๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎šฆ๎ด’๎ดŒ๎˜‚๎™Ž๎›พ๎ฑ๎ดŒ๎˜‚๎™Ž๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎™†๎ด’๎ดŒ๎˜‚๎™จ๎Ÿ›๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎› ๎žฟ๎ดŒ๎˜‚๎™ฆ๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎žฟ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎ด๎˜‚๎›ฐ๎‰๎žฟ๎ดŒ๎˜‚
๎˜ ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎œš๎ดค๎ด’๎˜‚๎šฃ๎ป๎žช๎Ž๎žท๎Ž๎Ÿ›๎œฉ๎˜‚๎žข๎›พ๎žท๎œฉ๎˜‚๎ป๎๎˜‚๎šฆ๎šผ๎ดฎ๎šฃ๎˜ ๎šฆ๎˜‚๎œข๎œฉ๎žท๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎˜‚๎ป๎๎˜‚
๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚ ๎Ž๎ฑ๎๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎˜‚ ๎Ž๎ฑ๎˜‚ ๎ฒ“๎ฒ—๎ฒ—๎ฒ๎˜‚ ๎œ›๎›พ๎žช๎œฉ๎žช๎˜‚ ๎๎žข๎ป๎ฏ๎˜‚ ๎ป๎ฑ๎œฉ๎˜‚
๎‰๎ป๎žช๎žŸ๎Ž๎žท๎›พ๎ฆ๎˜‚๎Ž๎ฑ๎˜‚๎› ๎žฟ๎‰๎›พ๎ฑ๎ดŒ๎˜‚๎˜ ๎‰๎Ž๎ฑ๎›พ๎ดŒ๎˜‚๎๎žข๎ป๎ฏ๎˜‚๎™ค๎›พ๎ฑ๎˜‚๎žท๎ป๎˜‚๎™†๎œฉ๎œš๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด’๎˜‚
Clinica Chimica๎˜‚ ๎˜ƒ๎œ›๎žท๎›พ๎ดŒ๎˜‚ ๎ฒ”๎ฒ๎ฒ”๎ดŒ๎˜‚ ๎ฒ๎ฒ–๎ฒ‘๎ดซ๎ฒ๎ฒ–๎ฒ”๎ด’๎˜‚ ๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎œข๎ป๎Ž๎ด’
org/10.1016/j.cca.2020.03.009
๎™ฒ๎›พ๎žข๎๎ฑ๎ดฎ๎šฎ๎›ฟ๎ฑ๎œ›๎‰๎œฉ๎Ÿฌ๎ดŒ๎˜‚ ๎™ฟ๎ด’๎ดŒ๎˜‚ ๎›Ÿ๎Ž๎Ÿ›๎›พ๎žช๎ดฎ๎šฆ๎žฟ๎Ž๎Ÿฌ๎ดŒ๎˜‚ ๎˜ง๎ด’๎ดŒ๎˜‚ ๎™ด๎œฉ๎Ž๎žข๎›พ๎ดŒ๎˜‚ ๎™ฒ๎ด’๎ดŒ๎˜‚
๎šฎ๎›พ๎ฑ๎œข๎ป๎Ÿ›๎›พ๎ฆ๎ดŒ๎˜‚๎™‡๎ด’๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎˜ ๎‰๎›พ๎œ›๎ผ๎ฑ๎ดŒ๎˜‚๎šฆ๎ด’๎˜‚๎˜ง๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎šฆ๎ป๎ฆ๎˜‚๎œข๎œฉ๎˜‚
los interferones tipo I y tipo III: Una revisiรณn de
conceptos. ๎˜„๎‚๎ป๎žข๎›พ๎˜‚๎šฆ๎œฉ๎Ÿ›๎Ž๎žช๎žท๎›พ๎˜‚๎˜ ๎Ž๎œฉ๎ฑ๎žท๎๎ ๎œ›๎›พ, 6(2), 2020.
๎™ฒ๎Ž๎ฑ๎Ž๎žช๎žท๎œฉ๎žข๎Ž๎ป๎˜‚ ๎œข๎œฉ๎˜‚ ๎šฎ๎›พ๎ฆ๎žฟ๎œข๎˜‚ ๎œข๎œฉ๎ฆ๎˜‚ ๎šฃ๎œฉ๎žข๎Ÿ€๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚ Sala Situacional
๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎šฃ๎œฉ๎žข๎Ÿ€๎ด’๎˜‚ ๎šฆ๎œฉ๎žท๎žข๎Ž๎œฉ๎Ÿ›๎œฉ๎œข๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚ ๎ฒ๎ฒ‘๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎๎žข๎ป๎ฏ๎˜‚
https://covid19.minsa.gob.pe/sala_situacional.
asp
๎™ด๎œฉ๎Ÿœ๎žท๎ป๎ฑ๎ดŒ๎˜‚๎˜ƒ๎ด’๎˜‚๎™Ž๎ด’๎ดŒ๎˜‚๎˜ ๎›พ๎žข๎œข๎›พ๎ฑ๎Ž๎ดŒ๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎˜Ÿ๎žข๎›พ๎œ›๎Ž๎›พ๎ฆ๎œฉ๎ดŒ๎˜‚๎šผ๎ด’๎˜‚๎™ค๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ•๎ดค๎ด’๎˜‚๎ ƒ๎œฉ๎˜‚๎‰๎ป๎žช๎žท๎˜‚
immune response in respiratory virus infection:
balancing virus clearance and immunopathology.
Seminars in Immunopathology, 38(4), 471โ€“482.
๎šฃ๎žข๎œฉ๎žช๎Ž๎œข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎˜‚๎œข๎œฉ๎˜‚ ๎ฆ๎›พ๎˜‚ ๎šฆ๎œฉ๎žŸ๎Ÿ€๎œš๎ฆ๎Ž๎œ›๎›พ๎˜‚๎œข๎œฉ๎ฆ๎˜‚ ๎šฃ๎œฉ๎žข๎Ÿ€๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚๎™ฒ๎›พ๎žข๎œ›๎‰๎˜‚๎ฒ•๎ดค๎ด’๎˜‚
Primer caso de infecciรณn por coronavirus en el Perรบ.
๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎‚๎ป๎œš๎ด’๎žŸ๎œฉ๎ด˜๎Ž๎ฑ๎žช๎žท๎Ž๎žท๎žฟ๎œ›๎Ž๎ป๎ฑ๎ด˜๎žŸ๎žข๎œฉ๎žช๎Ž๎œข๎œฉ๎ฑ๎œ›๎Ž๎›พ๎ด˜
๎ฑ๎ป๎žท๎Ž๎œ›๎Ž๎›พ๎žช๎ด˜๎ฒ—๎ฒ•๎ฒ˜๎ฒ–๎ฒ•๎ดฎ๎žŸ๎žข๎œฉ๎žช๎Ž๎œข๎œฉ๎ฑ๎žท๎œฉ๎ดฎ๎Ÿ›๎Ž๎Ÿฌ๎œ›๎›พ๎žข๎žข๎›พ๎ดฎ๎œข๎Ž๎ป๎ดฎ
a-conocer-primer-caso-de-infeccion-por-
๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎ดฎ๎œฉ๎ฑ๎ดฎ๎œฉ๎ฆ๎ดฎ๎žŸ๎œฉ๎žข๎žฟ๎ดฎ๎œฉ๎ดฎ๎‰๎Ž๎Ÿฌ๎ป๎ดฎ๎žฟ๎ฑ๎ดฎ๎ฆ๎ฆ๎›พ๎ฏ๎›พ๎œข๎ป๎ดฎ๎›พ๎ดฎ
la-poblacion-a-mantener-la-calma
๎šฎ๎‰๎œฉ๎žข๎œฉ๎œฉ๎ฑ๎ดŒ๎˜‚ ๎™ฒ๎ด’๎˜‚ ๎˜ƒ๎ด’๎ดŒ๎˜‚ ๎™ฆ๎‰๎›พ๎ฑ๎ดŒ๎˜‚ ๎šฎ๎ด’๎ดŒ๎˜‚ ๎™ฆ๎›พ๎Ÿฌ๎ฏ๎Ž๎ดŒ๎˜‚ ๎˜ƒ๎ด’๎ดŒ๎˜‚ ๎˜Ÿ๎›พ๎žช๎‰๎Ž๎žข๎ดŒ๎˜‚ ๎™ด๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚
๎šฎ๎Ž๎œข๎œข๎Ž๎žก๎žฟ๎œฉ๎ดŒ๎˜‚๎šฆ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚๎Ž๎ฑ๎๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎ด‹๎˜‚๎™ฟ๎žข๎Ž๎‚๎Ž๎ฑ๎ดŒ๎˜‚
transmission, and characteristics of human
coronaviruses. ๎™ค๎ป๎žฟ๎žข๎ฑ๎›พ๎ฆ๎˜‚๎ป๎๎˜‚๎˜ƒ๎œข๎Ÿ›๎œฉ๎žข๎žท๎Ž๎žช๎Ž๎ฑ๎‚๎˜‚๎šฆ๎œฉ๎žช๎œฉ๎›พ๎žข๎œ›๎‰, 24,
91โ€“98.
๎šฎ๎Ž๎žท๎žฟ๎›พ๎žท๎Ž๎ป๎ฑ๎›พ๎ฆ๎˜‚ ๎šฆ๎œฉ๎žŸ๎ป๎žข๎žท๎˜‚ ๎™Ž๎žฟ๎œš๎œฉ๎Ž๎˜‚ ๎šฃ๎žข๎ป๎Ÿ›๎Ž๎ฑ๎œ›๎œฉ๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎™†๎œฉ๎œš๎žข๎žฟ๎›พ๎žข๎Ÿข๎˜‚
๎ฒ๎ฒ’๎ดค๎ด’๎˜‚ ๎‰๎žท๎žท๎žŸ๎ด‹๎ด˜๎ด˜๎Ÿœ๎ ๎Ÿœ๎ด’๎‰๎žฟ๎œš๎œฉ๎Ž๎ด’๎‚๎ป๎Ÿ›๎ด’๎œ›๎ฑ๎ด˜๎Ÿด๎œš๎ ๎œข๎ด˜๎œข๎žท๎Ÿข๎Ÿœ๎ด˜๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ฒ๎ฒ‘๎ด˜
t20200213_2025581.shtml
๎šฎ๎ป๎ฑ๎‚๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎›ฅ๎žฟ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎˜Ÿ๎›พ๎ป๎ดŒ๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎›ฆ๎žฟ๎ดŒ๎˜‚๎šฃ๎ด’๎ดŒ๎˜‚๎šฅ๎žฟ๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚๎›ฐ๎‰๎žฟ๎ดŒ๎˜‚
๎™Ž๎ด’๎ดŒ๎˜‚ ๎›ฐ๎‰๎›พ๎ป๎ดŒ๎˜‚ ๎› ๎ด’๎ดŒ๎˜‚ ๎™Ž๎›พ๎ฑ๎ดŒ๎˜‚ ๎›ฆ๎ด’๎ดŒ๎˜‚ ๎ถฃ๎˜‚ ๎šฅ๎Ž๎ฑ๎ดŒ๎˜‚ ๎˜ ๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚ ๎™†๎žข๎ป๎ฏ๎˜‚
๎šฎ๎˜ƒ๎šฆ๎šฎ๎˜‚๎žท๎ป๎˜‚๎™ฒ๎˜ฏ๎šฆ๎šฎ๎ดŒ๎˜‚๎ ƒ๎žข๎žฟ๎žช๎žท๎Ž๎ฑ๎‚๎˜‚๎˜ ๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎œฉ๎žช๎˜‚๎Ž๎ฑ๎žท๎ป๎˜‚๎žท๎‰๎œฉ๎˜‚
๎šฎ๎žŸ๎ป๎žท๎ฆ๎Ž๎‚๎‰๎žท๎ด’๎˜‚ Viruses, 11(1). https://doi.org/10.3390/
v11010059
๎ ƒ๎›พ๎ฑ๎‰๎˜‚๎™จ๎œฉ๎ดŒ๎˜‚๎šผ๎ด’๎ดŒ๎˜‚๎˜ƒ๎ฑ๎œข๎žข๎œฉ๎›พ๎œข๎›พ๎ฃ๎Ž๎žช๎ดŒ๎˜‚๎›ฐ๎ด’๎ดŒ๎˜‚๎™ฆ๎žฟ๎ฏ๎›พ๎žข๎ดŒ๎˜‚๎˜ƒ๎ด’๎ดŒ๎˜‚๎™‡๎ผ๎ฏ๎œฉ๎Ÿฌ๎˜‚๎šฆ๎ป๎ฏ๎›ฟ๎ฑ๎ดŒ๎˜‚
๎šฆ๎ด’๎ดŒ๎˜‚๎šผ๎ป๎ฆ๎ฆ๎œฉ๎๎žช๎œฉ๎ฑ๎ดŒ๎˜‚๎šฎ๎ด’๎ดŒ๎˜‚๎šฎ๎›พ๎Ÿ›๎Ž๎ฆ๎ฆ๎œฉ๎ดŒ๎˜‚๎™ฒ๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎™ฒ๎›พ๎Ÿข๎‰๎œฉ๎Ÿœ๎ดŒ๎˜‚๎šฎ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚
๎ ƒ๎œฉ๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดฎ๎ฒ๎ฒ˜๎˜‚ ๎Ÿ›๎›พ๎œ›๎œ›๎Ž๎ฑ๎œฉ๎˜‚ ๎œข๎œฉ๎Ÿ›๎œฉ๎ฆ๎ป๎žŸ๎ฏ๎œฉ๎ฑ๎žท๎˜‚ ๎ฆ๎›พ๎ฑ๎œข๎žช๎œ›๎›พ๎žŸ๎œฉ๎ด’๎˜‚
๎™ด๎›พ๎žท๎žฟ๎žข๎œฉ๎˜‚ ๎šฆ๎œฉ๎Ÿ›๎Ž๎œฉ๎Ÿœ๎žช๎ด’๎˜‚ Drug Discovery. https://doi.
org/10.1038/d41573-020-00073-5
Cรกtedra Villarreal | Lima, perรบ | V. 8 | N. 1 |enero - junio| 2020 |e- issn 2311-2212 ๎ฒ‘๎ฒ’
WHO (2015). Consensus document on the epidemiology of
severe acute respiratory syndrome๎˜‚๎ดฃ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดค๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ”๎ดŒ๎˜‚๎™ค๎žฟ๎ฆ๎Ÿข๎˜‚
๎ฒ‘๎ฒ“๎ดค๎ด’๎˜‚ ๎› ๎ป๎žข๎ฆ๎œข๎˜‚ ๎™Ž๎œฉ๎›พ๎ฆ๎žท๎‰๎˜‚ ๎™ฟ๎žข๎‚๎›พ๎ฑ๎Ž๎Ÿฌ๎›พ๎žท๎Ž๎ป๎ฑ๎ด’๎˜‚ ๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’
๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎œ›๎žช๎žข๎ด˜๎žช๎›พ๎žข๎žช๎ด˜๎‚๎žฟ๎Ž๎œข๎œฉ๎ฆ๎Ž๎ฑ๎œฉ๎žช๎ด˜๎œฉ๎ฑ๎ด˜
WHO (2020a). Timeline - COVID-19๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚ ๎ฒ—๎ดค๎ด’๎˜‚
๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎ฑ๎œฉ๎Ÿœ๎žช๎ดฎ๎žข๎ป๎ป๎ฏ๎ด˜๎œข๎œฉ๎žท๎›พ๎Ž๎ฆ๎ด˜๎ฒ๎ฒ—๎ดฎ๎ฒ๎ฒ“๎ดฎ
๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดฎ๎Ÿœ๎‰๎ป๎ดฎ๎žท๎Ž๎ฏ๎œฉ๎ฆ๎Ž๎ฑ๎œฉ๎ดฎ๎ดฎ๎ดฎ๎œ›๎ป๎Ÿ›๎Ž๎œข๎ดฎ๎ฒ๎ฒ˜
WHO (2020b). Novel Coronavirus โ€“ China. (2020,
๎™ค๎›พ๎ฑ๎žฟ๎›พ๎žข๎Ÿข๎˜‚ ๎ฒ๎ฒ’๎ดค๎ด’๎˜‚ ๎‰๎žท๎žท๎žŸ๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎œ›๎žช๎žข๎ด˜๎œข๎ป๎ฑ๎ด˜๎ฒ๎ฒ‘๎ดฎ
january-2020-novel-coronavirus-china/en/
WHO (2020c). Naming the Coronavirus Disease (COVID-19)
๎›พ๎ฑ๎œข๎˜‚ ๎žท๎‰๎œฉ๎˜‚ ๎›Ÿ๎Ž๎žข๎žฟ๎žช๎˜‚ ๎ „๎›พ๎žท๎˜‚ ๎˜ ๎›พ๎žฟ๎žช๎œฉ๎žช๎˜‚ ๎™“๎žท๎ด’๎˜‚ ๎šฆ๎œฉ๎žท๎žข๎Ž๎œฉ๎Ÿ›๎œฉ๎œข๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚ ๎ฒ๎ฒ‘๎ดŒ๎˜‚
๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎๎žข๎ป๎ฏ๎˜‚ ๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎œฉ๎ฏ๎œฉ๎žข๎‚๎œฉ๎ฑ๎œ›๎Ž๎œฉ๎žช๎ด˜
diseases/novel-coronavirus-2019/technical-
guidance/naming-the-coronavirus-disease-
(covid-2019)-and-the-virus-that-causes-it
WHO (2020d). Middle East respiratory syndrome
coronavirus (MERS-CoV)๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎‰๎žท๎žท๎žŸ๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’
int/emergencies/mers-cov/en/
WHO (2020e). Coronavirus disease 2019 (COVID-19)
Situation Report โ€“ 46. (n.d.). World Health
Organization๎ด’๎˜‚ ๎šฆ๎œฉ๎žท๎žข๎Ž๎œฉ๎Ÿ›๎œฉ๎œข๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚ ๎ฒ๎ฒ‘๎ดŒ๎˜‚ ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎๎žข๎ป๎ฏ๎˜‚
๎‰๎žท๎žท๎žŸ๎žช๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎œฉ๎ฏ๎œฉ๎žข๎‚๎œฉ๎ฑ๎œ›๎Ž๎œฉ๎žช๎ด˜๎œข๎Ž๎žช๎œฉ๎›พ๎žช๎œฉ๎žช๎ด˜
novel-coronavirus-2019/situation-reports.
WHO (2020f). ๎˜ง๎žข๎›พ๎Ÿฝ๎žท๎˜‚ ๎ฆ๎›พ๎ฑ๎œข๎žช๎œ›๎›พ๎žŸ๎œฉ๎˜‚ ๎ป๎๎˜‚ ๎˜ ๎™ฟ๎›Ÿ๎™“๎˜ง๎ดด๎ฒ–๎ฒž๎˜‚ ๎œ›๎›พ๎ฑ๎œข๎Ž๎œข๎›พ๎žท๎œฉ๎˜‚
vaccines๎ด’๎˜‚ ๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดŒ๎˜‚ ๎˜ƒ๎žŸ๎žข๎Ž๎ฆ๎˜‚ ๎ฒ๎ฒ๎ดค๎ด’๎˜‚ ๎› ๎ป๎žข๎ฆ๎œข๎˜‚ ๎™Ž๎œฉ๎›พ๎ฆ๎žท๎‰๎˜‚
๎™ฟ๎žข๎‚๎›พ๎ฑ๎Ž๎Ÿฌ๎›พ๎žท๎Ž๎ป๎ฑ๎ด’๎˜‚ ๎‰๎žท๎žท๎žŸ๎ด‹๎ด˜๎ด˜๎Ÿœ๎Ÿœ๎Ÿœ๎ด’๎Ÿœ๎‰๎ป๎ด’๎Ž๎ฑ๎žท๎ด˜๎œš๎ฆ๎žฟ๎œฉ๎žŸ๎žข๎Ž๎ฑ๎žท๎ด˜
priority-diseases/key-action/novel-coronavirus/
en/
๎› ๎ป๎ฑ๎‚๎ดŒ๎˜‚๎˜ƒ๎ด’๎˜‚๎˜ ๎ด’๎˜‚๎šฃ๎ด’๎ดŒ๎˜‚๎™จ๎Ž๎ดŒ๎˜‚๎›ฅ๎ด’๎ดŒ๎˜‚๎™จ๎›พ๎žฟ๎ดŒ๎˜‚๎šฎ๎ด’๎˜‚๎™ฆ๎ด’๎˜‚๎šฃ๎ด’๎ดŒ๎˜‚๎ถฃ๎˜‚๎› ๎ป๎ป๎ดŒ๎˜‚๎šฃ๎ด’๎˜‚๎˜ ๎ด’๎˜‚๎›ฆ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎ดค๎ด’๎˜‚
๎™‡๎ฆ๎ป๎œš๎›พ๎ฆ๎˜‚ ๎˜ฏ๎žŸ๎Ž๎œข๎œฉ๎ฏ๎Ž๎ป๎ฆ๎ป๎‚๎Ÿข๎˜‚ ๎ป๎๎˜‚ ๎˜Ÿ๎›พ๎žท๎˜‚ ๎˜ ๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎œฉ๎žช๎ด’๎˜‚
Viruses, 11(2). https://doi.org/10.3390/v11020174
๎›ฆ๎žฟ๎ดŒ๎˜‚๎™†๎ด’๎ดŒ๎˜‚๎›ฆ๎›พ๎ฑ๎ดŒ๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™ด๎ด’๎ดŒ๎˜‚๎›ฆ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎šฎ๎ด’๎ดŒ๎˜‚๎› ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎™จ๎ด’๎ดŒ๎˜‚๎šผ๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎›ฆ๎ด’๎ดŒ๎˜‚
๎ด๎˜‚๎™†๎žฟ๎ ๎Ž๎œฉ๎˜‚๎›ฐ๎‰๎›พ๎ฑ๎‚๎ดŒ๎˜‚๎šฃ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด’๎ดค๎ด’๎˜‚๎šฅ๎žฟ๎›พ๎ฑ๎žท๎Ž๎žท๎›พ๎žท๎Ž๎Ÿ›๎œฉ๎˜‚๎˜ง๎œฉ๎žท๎œฉ๎œ›๎žท๎Ž๎ป๎ฑ๎˜‚
๎›พ๎ฑ๎œข๎˜‚ ๎›Ÿ๎Ž๎žข๎›พ๎ฆ๎˜‚ ๎™จ๎ป๎›พ๎œข๎˜‚ ๎˜ƒ๎ฑ๎›พ๎ฆ๎Ÿข๎žช๎Ž๎žช๎˜‚ ๎ป๎๎˜‚ ๎šฎ๎˜ƒ๎šฆ๎šฎ๎ดฎ๎˜ ๎ป๎›Ÿ๎ดฎ๎ฒ‘๎˜‚ ๎Ž๎ฑ๎˜‚
๎™“๎ฑ๎๎œฉ๎œ›๎žท๎œฉ๎œข๎˜‚ ๎šฃ๎›พ๎žท๎Ž๎œฉ๎ฑ๎žท๎žช๎ด’๎˜‚ Clinical Infectious Diseases;
ciaa345, https://doi.org/10.1093/cid/ciaa345
๎›ฐ๎‰๎›พ๎ป๎˜‚๎šฎ๎ดŒ๎˜‚et al๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎šฃ๎žข๎œฉ๎ฆ๎Ž๎ฏ๎Ž๎ฑ๎›พ๎žข๎Ÿข๎˜‚๎œฉ๎žช๎žท๎Ž๎ฏ๎›พ๎žท๎Ž๎ป๎ฑ๎˜‚๎ป๎๎˜‚๎žท๎‰๎œฉ๎˜‚๎œš๎›พ๎žช๎Ž๎œ›๎˜‚
reproduction number of novel coronavirus (2019-
๎ฑ๎˜ ๎ป๎›Ÿ๎ดค๎˜‚๎Ž๎ฑ๎˜‚๎˜ ๎‰๎Ž๎ฑ๎›พ๎ดŒ๎˜‚๎๎žข๎ป๎ฏ๎˜‚๎ฒ‘๎ฒ๎ฒ๎ฒ˜๎˜‚๎žท๎ป๎˜‚๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ด‹๎˜‚๎˜ƒ๎˜‚๎œข๎›พ๎žท๎›พ๎ดฎ๎œข๎žข๎Ž๎Ÿ›๎œฉ๎ฑ๎˜‚
analysis in the phase of an outbreak. ๎™“๎ฑ๎žท๎˜‚๎™ค๎˜‚๎™“๎ฑ๎๎œฉ๎œ›๎žท๎˜‚
Dis. 92; 214-217.
๎›ฐ๎‰๎ป๎žฟ๎ดŒ๎˜‚๎šฃ๎ด’๎˜‚๎œฉ๎žท๎˜‚๎›พ๎ฆ๎ด’๎˜‚๎ดฃ๎ฒ‘๎ฒ๎ฒ‘๎ฒ๎ดค๎ด’๎˜‚๎˜ƒ๎˜‚๎žŸ๎ฑ๎œฉ๎žฟ๎ฏ๎ป๎ฑ๎Ž๎›พ๎˜‚๎ป๎žฟ๎žท๎œš๎žข๎œฉ๎›พ๎ฃ๎˜‚๎›พ๎žช๎žช๎ป๎œ›๎Ž๎›พ๎žท๎œฉ๎œข๎˜‚
๎Ÿœ๎Ž๎žท๎‰๎˜‚ ๎›พ๎˜‚ ๎ฑ๎œฉ๎Ÿœ๎˜‚ ๎œ›๎ป๎žข๎ป๎ฑ๎›พ๎Ÿ›๎Ž๎žข๎žฟ๎žช๎˜‚ ๎ป๎๎˜‚ ๎žŸ๎žข๎ป๎œš๎›พ๎œš๎ฆ๎œฉ๎˜‚ ๎œš๎›พ๎žท๎˜‚ ๎ป๎žข๎Ž๎‚๎Ž๎ฑ๎ด’๎˜‚
Nature, 579 (2020); 270-273.